Protein information
  Protein summary    Phosphorylation site    Dephosphorylation site    Mutation site
  Differential expressed protein    Hyperphosphorylation site    Direct interaction pair    Function Annotation

Protein Summary
UniProt/SwissProt ID:GCFC2_HUMAN
Description:GC-rich sequence DNA-binding factor 2 [Source:HGNC Symbol;Acc:1317]
Location:chr2 p12
Node attribute:TF

Phosphorylation site
PositionPhosphoPeptideCatalytic kinaseSource
S436DDELPsAEMIDHPRD
S430QEGTSsDDELPGCFCPhosphoSitePlus
T192KRIPFtLRPQTPhosphoSitePlus
S106DKIHHsSESKDPhosphoSitePlus
S429HQEGTsSDDELGCFCPhosphoSitePlus
S180EDDPEsEPDDHPhosphoSitePlus; HPRD; phosphoELM
S252CGNGSsKVKKFPhosphoSitePlus
S637VENKTsPHSKFGCFCPhosphoSitePlus
S109HHSSEsKDDQGPhosphoSitePlus
S217ETSEEsQEDEKPhosphoSitePlus; HPRD; phosphoELM
S40LPVPGsAEEEPHPRD
Y376KHESTyLQQLSHPRD
S174GMKREsEDDPEPhosphoSitePlus; HPRD; phosphoELM
S19ADSSDsDGAEEPhosphoSitePlus; HPRD; phosphoELM
S251SCGNGsSKVKKPhosphoSitePlus
S262FDTSIsFPPVNHPRD
S430QEGTSsDDELPHPRD; phosphoELM
S214RNEETsEESQEPhosphoSitePlus; HPRD; phosphoELM
T428NHQEGtSSDDEGCFCPhosphoSitePlus
S16QRAADsSDSDGPhosphoSitePlus; HPRD; phosphoELM
S119GLSSDsSSSLGHPRD
S429HQEGTsSDDELHPRD; phosphoELM
S246RDIDLsCGNGSPhosphoSitePlus
Y681KLLNRyLIIALGCFCPhosphoSitePlus
T97TLDVStDEEDKPhosphoSitePlus; HPRD; phosphoELM
S17RAADSsDSDGAPhosphoSitePlus; HPRD; phosphoELM
T213SRNEEtSEESQPhosphoSitePlus; HPRD; phosphoELM
T259VKKFDtSISFPHPRD
T428NHQEGtSSDDEHPRD; phosphoELM
S96RTLDVsTDEEDPhosphoSitePlus; HPRD; phosphoELM

Dephosphorylation site
GCFC2_HUMAN do not have dephosphorylation site.

Mutation site
Ensembl IDVariationSourceCancer namePubmed
ENSP00000318690Q229*COSMICOvarian Cancer21720365
ENSP00000318690E108KCOSMICCentral Nervous System Neoplasms18772396

Differential expressed protein
GCFC2_HUMAN is not differential expressed protein.

Hyperphosphorylation site
GCFC2_HUMAN do not have hyperphosphorylation site.

Direct Interaction Pair
SourceTargetRelationshipResource
GCFC2_HUMANCAN2_HUMANTF -> target geneTRANSFAC
GCFC2_HUMANEGFR_HUMANTF -> target geneTRANSFAC

Function Annotation
KEGG Pathway
GCFC2_HUMAN is not in KEGG pathway.

Gene Ontology
GO IDGO_TermEvidenceOntology
GO:0003677DNA bindingIEAmolecular_function
GO:0005634nucleusIEAcellular_component
GO:0003700sequence-specific DNA binding transcription factorIEAmolecular_function
GO:0045892negative regulation of transcription, DNA-dependenNASbiological_process
GO:0006351transcription, DNA-dependentIEAbiological_process
GO:0006355regulation of transcription, DNA-dependentNASbiological_process


Fatal error: Uncaught Error: Call to undefined function mysql_close() in /usr/local/apache/htdocs/PhoSigNet/include/locateconfig.inc.php:23 Stack trace: #0 /usr/local/apache/htdocs/PhoSigNet/proteintable.php(435): db_disconnect(Object(mysqli)) #1 {main} thrown in /usr/local/apache/htdocs/PhoSigNet/include/locateconfig.inc.php on line 23