| UniProt/SwissProt ID: | FPR2_HUMAN |
| Description: | formyl peptide receptor 2 [Source:HGNC Symbol;Acc:3827] |
| Location: | chr19 q13.41 |
| Node attribute: | receptor |
| Phosphorylation site |
| Position | PhosphoPeptide | Catalytic kinase | Source |
|---|---|---|---|
| T332 | EDSAPtNDTAA | PhosphoSitePlus | |
| S236 | KGMIKsSRPLR | HPRD; phosphoELM | |
| S329 | ALSEDsAPTND | PhosphoSitePlus | |
| S237 | GMIKSsRPLRV | 7tm_1 | PhosphoSitePlus |
| T335 | APTNDtAANSA | PhosphoSitePlus | |
| S236 | KGMIKsSRPLR | 7tm_1 | PhosphoSitePlus |
| S316 | ERLIHsLPTSL | PhosphoSitePlus | |
| Y302 | LNPMLyVFVGQ | HPRD; phosphoELM | |
| S237 | GMIKSsRPLRV | HPRD; phosphoELM | |
| Y302 | LNPMLyVFVGQ | TM; 7tm_1 | PhosphoSitePlus |
| Dephosphorylation site |
| FPR2_HUMAN do not have dephosphorylation site. |
| Mutation site |
| Ensembl ID | Variation | Source | Cancer name | Pubmed |
|---|---|---|---|---|
| ENSP00000340191 | W183* | COSMIC | Lung Cancer | 20668451 | ENSP00000340191 | L39F | COSMIC | Head and Neck Cancer | 21984974 | ENSP00000340191 | T332I | COSMIC | Lung Cancer | 20668451 | ENSP00000340191 | R238C | COSMIC | Skin Cancer | 21984974 | ENSP00000340191 | P256S | COSMIC | Skin Cancer | 21984974 |
| Differential expressed protein |
| FPR2_HUMAN is not differential expressed protein. |
| Hyperphosphorylation site |
| FPR2_HUMAN do not have hyperphosphorylation site. |
| Direct Interaction Pair |
| Source | Target | Relationship | Resource |
|---|---|---|---|
| CHAP1_HUMAN | FPR2_HUMAN | ligand -> receptor | HPMR |
| Function Annotation |
| KEGG Pathway |
| KEGG ID | Pathway |
|---|---|
| hsa04080 | Neuroactive ligand-receptor interaction |
| hsa05150 | Staphylococcus aureus infection |
| Gene Ontology |
| GO ID | GO_Term | Evidence | Ontology |
|---|---|---|---|
| GO:0006935 | chemotaxis | IEA | biological_process |
| GO:0006954 | inflammatory response | TAS | biological_process |
| GO:0007186 | G-protein coupled receptor signaling pathway | TAS | biological_process |
| GO:0004982 | N-formyl peptide receptor activity | IEA | molecular_function |
| GO:0005886 | plasma membrane | TAS | cellular_component |
| GO:0004930 | G-protein coupled receptor activity | TAS | molecular_function |
| GO:0016021 | integral to membrane | IEA | cellular_component |
| GO:0006928 | cellular component movement | TAS | biological_process |
| GO:0007155 | cell adhesion | TAS | biological_process |