Protein information
  Protein summary    Phosphorylation site    Dephosphorylation site    Mutation site
  Differential expressed protein    Hyperphosphorylation site    Direct interaction pair    Function Annotation

Protein Summary
UniProt/SwissProt ID:CHAP1_HUMAN
Description:chromosome alignment maintaining phosphoprotein 1 [Source:HGNC Symbol;Acc:20311]
Location:chr13 q34
Node attribute:ligand

Phosphorylation site
PositionPhosphoPeptideCatalytic kinaseSource
S633DAELSsSEYIKPhosphoSitePlus; HPRD; phosphoELM
S247ASSPEsPVLAAPhosphoSitePlus
S436RSPAGsPELRKPhosphoSitePlus; HPRD; phosphoELM
S432SPEIRsPAGSPPhosphoSitePlus; HPRD; phosphoELM
S627DNQESsDAELSPhosphoSitePlus; HPRD; phosphoELM
S223VKATLsNPKPQPhosphoSitePlus; HPRD
S173QTPLPsPEPSKPhosphoSitePlus
S427PGPPLsPEIRSPhosphoSitePlus; HPRD; phosphoELM
S253PVLAAsPEPWGPhosphoSitePlus
S386KSPPAsPESWKPhosphoSitePlus; HPRD; phosphoELM
S297PFPAVsPEPRRPhosphoSitePlus; HPRD; phosphoELM
T458PDQRKtSPASLPhosphoSitePlus; HPRD; phosphoELM
S462KTSPAsLDFPEPhosphoSitePlus; HPRD; phosphoELM
S284RKPSPsESPEPPhosphoSitePlus; HPRD; phosphoELM
S626KDNQEsSDAELPhosphoSitePlus; HPRD; phosphoELM
S651IKGQEsSSDQEPhosphoSitePlus; HPRD; phosphoELM
S311AVSPGsWKPGPPhosphoSitePlus
S675KMDMTsPEQSRPhosphoSitePlus; HPRD
S452DLWKLsPDQRKPhosphoSitePlus; HPRD; phosphoELM
T152KPTPLtPLEPQPhosphoSitePlus
S507SGPSEsPKAASPhosphoSitePlus; HPRD; phosphoELM
S217PVSPEsVKATLPhosphoSitePlus; HPRD; phosphoELM
S355PIPSVsPGPWKPhosphoSitePlus; HPRD
S108TDPVKsPPLPEPhosphoSitePlus; HPRD; phosphoELM
S416AVPPVsPELRKPhosphoSitePlus; HPRD; phosphoELM
T149ESPKPtPLTPLPhosphoSitePlus
S264PSPAAsPESRKPhosphoSitePlus
S615DTLFPsSKKLKPhosphoSitePlus; HPRD
S376KSSSVsPSSWKPhosphoSitePlus; HPRD
T403RKTAPtLSPEHPhosphoSitePlus
T169SPELQtPLPSPPhosphoSitePlus
S634AELSSsEYIKTPhosphoSitePlus; HPRD; phosphoELM
S570KSALFsESQKAPhosphoSitePlus
S344PAPSVsPGPWKPhosphoSitePlus; HPRD
S445RKPSGsPDLWKPhosphoSitePlus; HPRD; phosphoELM
S379SVSPSsWKSPPPhosphoSitePlus
S374SWKSSsVSPSSPhosphoSitePlus
S476SSRGGsPDLWKPhosphoSitePlus; HPRD; phosphoELM
T362GPWKPtPSVSSHPRD
S566PELPKsALFSEPhosphoSitePlus; HPRD
S736KHNVHsPYKCTPhosphoSitePlus; HPRD
S405TAPTLsPEHWKPhosphoSitePlus; HPRD; phosphoELM
S694KEAFIsEEEIAPhosphoSitePlus
T785FKKHLtHCQSRPhosphoSitePlus
S139TQKLGsVLSPEHPRD; phosphoELM
S389PASPEsWKSGPPhosphoSitePlus
S632SDAELsSSEYIPhosphoSitePlus; HPRD; phosphoELM
T400PELRKtAPTLSPhosphoSitePlus
S572ALFSEsQKAVEPhosphoSitePlus
S542TAPPAsPEARKPhosphoSitePlus; HPRD; phosphoELM
S372SASWKsSSVSPPhosphoSitePlus
S616TLFPSsKKLKKHPRD
S653GQESSsDQEQVPhosphoSitePlus; HPRD; phosphoELM
S319PGPPGsPRPWKPhosphoSitePlus; HPRD; phosphoELM
S373ASWKSsSVSPSPhosphoSitePlus
S286PSPSEsPEPWKPhosphoSitePlus; HPRD; phosphoELM
S87TSKHAsPDKWNPhosphoSitePlus; HPRD; phosphoELM
S145VLSPEsPKPTPPhosphoSitePlus
S468LDFPEsQKSSRPhosphoSitePlus
S275SARTTsPEPRKPhosphoSitePlus; HPRD; phosphoELM
S204LAPVPsPEPQKPhosphoSitePlus; HPRD; phosphoELM
S392PESWKsGPPELPhosphoSitePlus
S378SSVSPsSWKSPPhosphoSitePlus
S308PAPAVsPGSWKPhosphoSitePlus; HPRD; phosphoELM
S184PASVSsPEPPKPhosphoSitePlus
S459DQRKTsPASLDPhosphoSitePlus; HPRD; phosphoELM
S652KGQESsSDQEQPhosphoSitePlus; HPRD; phosphoELM
S142LGSVLsPESPKPhosphoSitePlus
T103QLNKEtDPVKSPhosphoSitePlus; HPRD
S282EPRKPsPSESPPhosphoSitePlus; HPRD; phosphoELM
S603EELLAsPKKLLPhosphoSitePlus; HPRD; phosphoELM
S260EPWGPsPAASPPhosphoSitePlus
S505GPSGPsESPKAPhosphoSitePlus; HPRD; phosphoELM
S472ESQKSsRGGSPPhosphoSitePlus; HPRD; phosphoELM
S214KPAPVsPESVKPhosphoSitePlus; HPRD; phosphoELM
S483DLWKSsFFIEPPhosphoSitePlus
S471PESQKsSRGGSPhosphoSitePlus
T274KSARTtSPEPRPhosphoSitePlus
S382PSSWKsPPASPPhosphoSitePlus; HPRD; phosphoELM
S443ELRKPsGSPDLPhosphoSitePlus; HPRD

Dephosphorylation site
CHAP1_HUMAN do not have dephosphorylation site.

Mutation site
Ensembl IDVariationSourceCancer namePubmed
ENSP00000354730D89HCOSMICOvarian Cancer21720365
ENSP00000354730G474RCOSMICOvarian Cancer21720365
ENSP00000354730P543SCOSMICSkin Cancer21984974
ENSP00000354730H32YCOSMICSkin Cancer21984974
ENSP00000354730Q590EBIOMARTGastric Cancer21930507, 21930502

Differential expressed protein
CHAP1_HUMAN is not differential expressed protein.

Hyperphosphorylation site
CHAP1_HUMAN do not have hyperphosphorylation site.

Direct Interaction Pair
SourceTargetRelationshipResource
CHAP1_HUMANFPR2_HUMANligand -> receptorHPMR

Function Annotation
KEGG Pathway
CHAP1_HUMAN is not in KEGG pathway.

Gene Ontology
GO IDGO_TermEvidenceOntology
GO:0003676nucleic acid bindingIEAmolecular_function
GO:0000793condensed chromosomeIDAcellular_component
GO:0005515protein bindingIPImolecular_function
GO:0051315attachment of spindle microtubules to kinetochore IMPbiological_process
GO:0005819spindleIDAcellular_component
GO:0034501protein localization to kinetochoreIMPbiological_process
GO:0005622intracellularIEAcellular_component
GO:0035372protein localization to microtubuleIMPbiological_process
GO:0008270zinc ion bindingIEAmolecular_function
GO:0005737cytoplasmIEAcellular_component
GO:0031134sister chromatid biorientationIMPbiological_process
GO:0000777condensed chromosome kinetochoreIDAcellular_component
GO:0005634nucleusIDAcellular_component