Protein information
  Protein summary    Phosphorylation site    Dephosphorylation site    Mutation site
  Differential expressed protein    Hyperphosphorylation site    Direct interaction pair    Function Annotation

Protein Summary
UniProt/SwissProt ID:FOXN3_HUMAN
Description:forkhead box N3 [Source:HGNC Symbol;Acc:1928]
Location:chr14 q32.11
Node attribute:substrate

Phosphorylation site
PositionPhosphoPeptideCatalytic kinaseSource
T297RPLPItPIGVTPhosphoSitePlus
S8PVMPPsKKPESPhosphoSitePlus
T316SCRMRtESEPSPhosphoSitePlus
S97DDTPPsPAHSDPhosphoSitePlus
S432ARKVPsDTLPLPhosphoSitePlus
S318RMRTEsEPSCGPhosphoSitePlus
S83ESVLRsVSPVQPhosphoSitePlus
S101PSPAHsDMPYDPhosphoSitePlus
S324EPSCGsPVVSGPhosphoSitePlus
S85VLRSVsPVQDLPhosphoSitePlus

Dephosphorylation site
FOXN3_HUMAN do not have dephosphorylation site.

Mutation site
Ensembl IDVariationSourceCancer namePubmed
ENSP00000452227T412ICOSMICOvarian Cancer21720365
ENSP00000452227D42ECOSMICHead and Neck Cancer21798893
ENSP00000452227S79LCOSMICMelanoma21499247
ENSP00000452005S336FCOSMICMelanoma
ENSP00000452005D42ECOSMICHead and Neck Cancer21798893
ENSP00000452005T412ICOSMICOvarian Cancer21720365
ENSP00000452227S336FCOSMICMelanoma
ENSP00000452005S79LCOSMICMelanoma21499247

Differential expressed protein
FOXN3_HUMAN is not differential expressed protein.

Hyperphosphorylation site
FOXN3_HUMAN do not have hyperphosphorylation site.

Direct Interaction Pair
SourceTargetRelationshipResource
PKN1_HUMANFOXN3_HUMANkinase -> substrateRobert H Newman (2013)
AKT1_HUMANFOXN3_HUMANkinase -> substrateRobert H Newman (2013)

Function Annotation
KEGG Pathway
FOXN3_HUMAN is not in KEGG pathway.

Gene Ontology
GO IDGO_TermEvidenceOntology
GO:0005634nucleusIEAcellular_component
GO:0006351transcription, DNA-dependentIEAbiological_process
GO:0008301DNA binding, bendingIBAmolecular_function
GO:0000077DNA damage checkpointTASbiological_process
GO:0005667transcription factor complexIBAcellular_component
GO:0003705RNA polymerase II distal enhancer sequence-specifiIBAmolecular_function
GO:0003690double-stranded DNA bindingIBAmolecular_function
GO:0008134transcription factor bindingIBAmolecular_function
GO:0009790embryo developmentIBAbiological_process
GO:0045892negative regulation of transcription, DNA-dependenIDAbiological_process
GO:0007389pattern specification processIBAbiological_process
GO:0009888tissue developmentIBAbiological_process
GO:0006355regulation of transcription, DNA-dependentIEAbiological_process
GO:0043565sequence-specific DNA bindingIEAmolecular_function
GO:0005515protein bindingIPImolecular_function
GO:0000085G2 phase of mitotic cell cycleTASbiological_process
GO:0003700sequence-specific DNA binding transcription factorIEAmolecular_function
GO:0051090regulation of sequence-specific DNA binding transcIBAbiological_process
GO:0008022protein C-terminus bindingIPImolecular_function


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