| UniProt/SwissProt ID: | FOXJ2_HUMAN |
| Description: | forkhead box J2 [Source:HGNC Symbol;Acc:24818] |
| Location: | chr12 p13.31 |
| Node attribute: | TF |
| Phosphorylation site |
| Position | PhosphoPeptide | Catalytic kinase | Source |
|---|---|---|---|
| S31 | KLGSAsQAGPP | PhosphoSitePlus; HPRD | |
| S197 | QMSLQsPTSIA | HPRD | |
| S7 | LTSI | HPRD | |
| S172 | QEASKsPRGGV | PhosphoSitePlus; HPRD | |
| T48 | SPGSPtDPNAT | HPRD | |
| S46 | KCSPGsPTDPN | HPRD | |
| S261 | RNLYKsMLEKS | PhosphoSitePlus; HPRD; phosphoELM | |
| S43 | SSRKCsPGSPT | PhosphoSitePlus; HPRD | |
| S3 | ___MAsDLESS | PhosphoSitePlus | |
| T53 | TDPNAtLSKDE | HPRD | |
| S170 | PEQEAsKSPRG | PhosphoSitePlus | |
| S3 | LESS | HPRD | |
| T23 | LTLRAtIEKLG | PhosphoSitePlus; HPRD | |
| S29 | IEKLGsASQAG | PhosphoSitePlus | |
| S164 | DLSQDsPEQEA | PhosphoSitePlus; HPRD | |
| Y259 | SFRNLyKSMLE | PhosphoSitePlus; HPRD; phosphoELM | |
| S254 | QDLSWsFRNLY | PhosphoSitePlus | |
| S161 | PDDDLsQDSPE | PhosphoSitePlus; HPRD; phosphoELM | |
| Dephosphorylation site |
| FOXJ2_HUMAN do not have dephosphorylation site. |
| Mutation site |
| Ensembl ID | Variation | Source | Cancer name | Pubmed |
|---|---|---|---|---|
| ENSP00000162391 | P173L | COSMIC | Skin Cancer | 21984974 | ENSP00000162391 | D57H | COSMIC | Head and Neck Cancer | 21798897 | ENSP00000162391 | R223* | COSMIC | Skin Cancer | 21984974 | ENSP00000162391 | K86N | COSMIC | Head and Neck Cancer | 21798897 | ENSP00000162391 | P335A | TCGA | Ovarian Cancer | 21720365, 18772890 | ENSP00000162391 | G279R | TCGA, COSMIC | Ovarian Cancer | 21720365, 18772890 | ENSP00000162391 | P335A | COSMIC | Ovarian Cancer | 21720365 |
| Differential expressed protein |
| FOXJ2_HUMAN is not differential expressed protein. |
| Hyperphosphorylation site |
| FOXJ2_HUMAN do not have hyperphosphorylation site. |
| Direct Interaction Pair |
| Source | Target | Relationship | Resource |
|---|---|---|---|
| FOXJ2_HUMAN | C4BPA_HUMAN | TF -> target gene | TRANSFAC |
| Function Annotation |
| KEGG Pathway |
| FOXJ2_HUMAN is not in KEGG pathway. |
| Gene Ontology |
| GO ID | GO_Term | Evidence | Ontology |
|---|---|---|---|
| GO:0045893 | positive regulation of transcription, DNA-dependen | IDA | biological_process |
| GO:0003700 | sequence-specific DNA binding transcription factor | IEA | molecular_function |
| GO:0005634 | nucleus | IDA | cellular_component |
| GO:0005730 | nucleolus | IDA | cellular_component |
| GO:0009790 | embryo development | IBA | biological_process |
| GO:0051090 | regulation of sequence-specific DNA binding transc | IBA | biological_process |
| GO:0007389 | pattern specification process | IBA | biological_process |
| GO:0048513 | organ development | IBA | biological_process |
| GO:0008134 | transcription factor binding | IBA | molecular_function |
| GO:0003690 | double-stranded DNA binding | IBA | molecular_function |
| GO:0006355 | regulation of transcription, DNA-dependent | IEA | biological_process |
| GO:0003705 | RNA polymerase II distal enhancer sequence-specifi | IBA | molecular_function |
| GO:0043565 | sequence-specific DNA binding | IEA | molecular_function |
| GO:0008301 | DNA binding, bending | IBA | molecular_function |
| GO:0005667 | transcription factor complex | IBA | cellular_component |
| GO:0009888 | tissue development | IBA | biological_process |
| GO:0019904 | protein domain specific binding | IBA | molecular_function |