| UniProt/SwissProt ID: | FOSL2_HUMAN |
| Description: | FOS-like antigen 2 [Source:HGNC Symbol;Acc:3798] |
| Location: | chr2 p23.2 |
| Node attribute: | TF |
| Phosphorylation site |
| Position | PhosphoPeptide | Catalytic kinase | Source |
|---|---|---|---|
| S79 | NPYPRsHPYSP | PhosphoSitePlus; HPRD | |
| S211 | LQPMRsGGGSV | PhosphoSitePlus; HPRD; phosphoELM | |
| S308 | AHRRSsSSGDQ | PhosphoSitePlus; HPRD; phosphoELM | |
| S309 | HRRSSsSGDQS | PhosphoSitePlus; HPRD; phosphoELM | |
| S235 | SPSSSsAGLDK | HPRD; phosphoELM | |
| S200 | PEERRsPPAPG | PhosphoSitePlus; HPRD; phosphoELM | |
| S232 | EEDSPsSSSAG | PhosphoSitePlus; HPRD; phosphoELM | |
| S230 | PLEEDsPSSSS | PhosphoSitePlus; HPRD; phosphoELM | |
| S83 | RSHPYsPLPGL | PhosphoSitePlus; HPRD; phosphoELM | |
| S310 | RRSSSsGDQSS | HPRD; phosphoELM | |
| S17 | SSRGSsGSPAH | HPRD | |
| S320 | SDSLNsPTLL | HPRD | |
| S215 | RSGGGsVGAVV | HPRD; phosphoELM | |
| S320 | SDSLNsPTLLA | PhosphoSitePlus | |
| S233 | EDSPSsSSAGL | HPRD | |
| S317 | DQSSDsLNSPT | PhosphoSitePlus | |
| S16 | TSSRGsSGSPA | HPRD; phosphoELM | |
| S307 | KAHRRsSSSGD | PhosphoSitePlus; HPRD | |
| S120 | RDEQLsPEEEE | PhosphoSitePlus; HPRD | |
| Y76 | SMSNPyPRSHP | PhosphoSitePlus | |
| S19 | RGSSGsPAHAE | HPRD; phosphoELM | |
| T322 | SLNSPtLL | HPRD | |
| Dephosphorylation site |
| FOSL2_HUMAN do not have dephosphorylation site. |
| Mutation site |
| Ensembl ID | Variation | Source | Cancer name | Pubmed |
|---|---|---|---|---|
| ENSP00000264716 | L206M | COSMIC | Skin Cancer | 21984974 | ENSP00000264716 | E289Q | TCGA | Ovarian Cancer | 21720365, 18772890 | ENSP00000264716 | E150K | TCGA | Ovarian Cancer | 21720365, 18772890 | ENSP00000264716 | E289Q | COSMIC | Ovarian Cancer | 21720365 | ENSP00000264716 | E150K | COSMIC | Ovarian Cancer | 21720365 |
| Differential expressed protein |
| FOSL2_HUMAN is not differential expressed protein. |
| Hyperphosphorylation site |
| FOSL2_HUMAN do not have hyperphosphorylation site. |
| Direct Interaction Pair |
| Source | Target | Relationship | Resource |
|---|---|---|---|
| FOSL2_HUMAN | IL5_HUMAN | TF -> target gene | TRANSFAC |
| FOSL2_HUMAN | FOSL1_HUMAN | TF -> target gene | TRANSFAC |
| Function Annotation |
| KEGG Pathway |
| FOSL2_HUMAN is not in KEGG pathway. |
| Gene Ontology |
| GO ID | GO_Term | Evidence | Ontology |
|---|---|---|---|
| GO:0000977 | RNA polymerase II regulatory region sequence-speci | IEA | molecular_function |
| GO:0006351 | transcription, DNA-dependent | IEA | biological_process |
| GO:0003700 | sequence-specific DNA binding transcription factor | IEA | molecular_function |
| GO:0043565 | sequence-specific DNA binding | IEA | molecular_function |
| GO:0008219 | cell death | TAS | biological_process |
| GO:0003677 | DNA binding | IEA | molecular_function |
| GO:0048146 | positive regulation of fibroblast proliferation | IEA | biological_process |
| GO:0006357 | regulation of transcription from RNA polymerase II | TAS | biological_process |
| GO:0005634 | nucleus | IEA | cellular_component |
| GO:0006355 | regulation of transcription, DNA-dependent | IEA | biological_process |
| GO:0005634 | nucleus | IDA | cellular_component |