Protein information
  Protein summary    Phosphorylation site    Dephosphorylation site    Mutation site
  Differential expressed protein    Hyperphosphorylation site    Direct interaction pair    Function Annotation

Protein Summary
UniProt/SwissProt ID:FLI1_HUMAN
Description:Friend leukemia virus integration 1 [Source:HGNC Symbol;Acc:3749]
Location:chr11 q24.3
Node attribute:TF

Phosphorylation site
PositionPhosphoPeptideCatalytic kinaseSource
S89SVSKCsKLVGGPhosphoSitePlus; HPRD; phosphoELM
Y332KPNMNyDKLSREtsPhosphoSitePlus
Y42SGSPDyGQPHKPhosphoSitePlus
S39MTASGsPDYGQPhosphoSitePlus
S221VKEDPsYDSVRPhosphoSitePlus
Y451SHLGSyY____PhosphoSitePlus
S76DHMNGsRESPVPhosphoSitePlus; HPRD; phosphoELM
S236GNNMNsGLNKSPhosphoSitePlus
Y452HLGSYy_____PhosphoSitePlus
S224DPSYDsVRRGAPhosphoSitePlus
S86VDCSVsKCSKLPhosphoSitePlus; HPRD; phosphoELM
S241SGLNKsPPLGGPhosphoSitePlus
S450PSHLGsYY___PhosphoSitePlus
Y222KEDPSyDSVRRPhosphoSitePlus
Y263PQPDPyQILGPPhosphoSitePlus
T312GEFKMtDPDEVEtsPhosphoSitePlus

Dephosphorylation site
FLI1_HUMAN do not have dephosphorylation site.

Mutation site
Ensembl IDVariationSourceCancer namePubmed
ENSP00000399985I365TCOSMICLung Cancer20668451
ENSP00000399985V410ICOSMICCentral Nervous System Neoplasms18772890
ENSP00000399985G94ECOSMICCentral Nervous System Neoplasms18772890
ENSP00000399985R68WCOSMICLung Cancer20668451
ENSP00000399985H394RCOSMICOvarian Cancer21720365

Differential expressed protein
FLI1_HUMAN is not differential expressed protein.

Hyperphosphorylation site
SiteMotifPeptideCancer namePubmedSource
T312EtsTNGEFKMtDPDEVARscleroderma21321929PhosphoSitePlus

Direct Interaction Pair
SourceTargetRelationshipResource
FLI1_HUMANEGR1_HUMANTF -> target geneTRANSFAC
FLI1_HUMANFOS_HUMANTF -> target geneTRANSFAC

Function Annotation
KEGG Pathway
FLI1_HUMAN is not in KEGG pathway.

Gene Ontology
GO IDGO_TermEvidenceOntology
GO:0009887organ morphogenesisIEAbiological_process
GO:0043565sequence-specific DNA bindingIEAmolecular_function
GO:0006355regulation of transcription, DNA-dependentIEAbiological_process
GO:0005634nucleusIEAcellular_component
GO:0000980RNA polymerase II distal enhancer sequence-specifiIEAmolecular_function
GO:0008015blood circulationIEAbiological_process
GO:0007599hemostasisTASbiological_process
GO:0003700sequence-specific DNA binding transcription factorIEAmolecular_function
GO:0003677DNA bindingTASmolecular_function
GO:0006351transcription, DNA-dependentIEAbiological_process


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