Protein information
  Protein summary    Phosphorylation site    Dephosphorylation site    Mutation site
  Differential expressed protein    Hyperphosphorylation site    Direct interaction pair    Function Annotation

Protein Summary
UniProt/SwissProt ID:FGF4_HUMAN
Description:fibroblast growth factor 4 [Source:HGNC Symbol;Acc:3682]
Location:chr11 q13.3
Node attribute:ligand

Phosphorylation site
PositionPhosphoPeptideCatalytic kinaseSource
T196NRVSPtMKVTHFGFPhosphoSitePlus
S54SLVALsLARLPPhosphoSitePlus

Dephosphorylation site
FGF4_HUMAN do not have dephosphorylation site.

Mutation site
FGF4_HUMAN do not have mutation site.

Differential expressed protein
FGF4_HUMAN is not differential expressed protein.

Hyperphosphorylation site
FGF4_HUMAN do not have hyperphosphorylation site.

Direct Interaction Pair
SourceTargetRelationshipResource
FGF4_HUMANFGFR3_HUMANligand -> receptorHPMR
FGF4_HUMANFGFR2_HUMANligand -> receptorHPMR
FGF4_HUMANFGFR4_HUMANligand -> receptorHPMR
FGF4_HUMANFGFR1_HUMANligand -> receptorHPMR

Function Annotation
KEGG Pathway
KEGG IDPathway
hsa05200Pathways in cancer
hsa04010MAPK signaling pathway
hsa05218Melanoma
hsa04810Regulation of actin cytoskeleton

Gene Ontology
GO IDGO_TermEvidenceOntology
GO:0005515protein bindingIEAmolecular_function
GO:0008543fibroblast growth factor receptor signaling pathwaIEAbiological_process
GO:0060363cranial suture morphogenesisIEAbiological_process
GO:0005576extracellular regionTAScellular_component
GO:0010463mesenchymal cell proliferationIDAbiological_process
GO:0005104fibroblast growth factor receptor bindingIEAmolecular_function
GO:0005634nucleusIEAcellular_component
GO:0005829cytosolIEAcellular_component
GO:0008543fibroblast growth factor receptor signaling pathwaIGIbiological_process
GO:0030326embryonic limb morphogenesisIEAbiological_process
GO:0007165signal transductionTASbiological_process
GO:0060591chondroblast differentiationIDAbiological_process
GO:0008284positive regulation of cell proliferationIGIbiological_process
GO:0010628positive regulation of gene expressionIEAbiological_process
GO:0008284positive regulation of cell proliferationIEAbiological_process
GO:0043066negative regulation of apoptotic processIEAbiological_process
GO:0042475odontogenesis of dentin-containing toothIEAbiological_process
GO:0010468regulation of gene expressionIEAbiological_process
GO:0008201heparin bindingIEAmolecular_function
GO:0051781positive regulation of cell divisionIEAbiological_process
GO:0019827stem cell maintenanceIEAbiological_process
GO:0045944positive regulation of transcription from RNA polyIEAbiological_process
GO:0035116embryonic hindlimb morphogenesisIEAbiological_process
GO:0001502cartilage condensationIEAbiological_process
GO:0008286insulin receptor signaling pathwayTASbiological_process
GO:0007267cell-cell signalingTASbiological_process
GO:0070374positive regulation of ERK1 and ERK2 cascadeIDAbiological_process
GO:0001934positive regulation of protein phosphorylationIEAbiological_process
GO:0060561apoptotic process involved in morphogenesisIEAbiological_process
GO:0008083growth factor activityIEAmolecular_function


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