Protein information
  Protein summary    Phosphorylation site    Dephosphorylation site    Mutation site
  Differential expressed protein    Hyperphosphorylation site    Direct interaction pair    Function Annotation

Protein Summary
UniProt/SwissProt ID:FBX3_HUMAN
Description:F-box protein 3 [Source:HGNC Symbol;Acc:13582]
Location:chr11 p13
Node attribute:substrate

Phosphorylation site
PositionPhosphoPeptideCatalytic kinaseSource
Y223KNEVFyQCPDQSMI1_KNR4PhosphoSitePlus
Y420MGPDEyEEMEEPhosphoSitePlus
S166GSMALsNHYRSSMI1_KNR4PhosphoSitePlus

Dephosphorylation site
FBX3_HUMAN do not have dephosphorylation site.

Mutation site
Ensembl IDVariationSourceCancer namePubmed
ENSP00000408836S287LBIOMARTBreast Cancer21930507, 21930502
ENSP00000265651S287LBIOMARTBreast Cancer21930507, 21930502
ENSP00000265651V177ICOSMICPancreatic Cancer

Differential expressed protein
FBX3_HUMAN is not differential expressed protein.

Hyperphosphorylation site
FBX3_HUMAN do not have hyperphosphorylation site.

Direct Interaction Pair
SourceTargetRelationshipResource
MK08_HUMANFBX3_HUMANkinase -> substrateRobert H Newman (2013)

Function Annotation
KEGG Pathway
FBX3_HUMAN is not in KEGG pathway.

Gene Ontology
GO IDGO_TermEvidenceOntology
GO:0005634nucleusIEAcellular_component
GO:0005515protein bindingIPImolecular_function
GO:0004842ubiquitin-protein ligase activityTASmolecular_function
GO:0006508proteolysisTASbiological_process
GO:0016567protein ubiquitinationTASbiological_process


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