Protein information
  Protein summary    Phosphorylation site    Dephosphorylation site    Mutation site
  Differential expressed protein    Hyperphosphorylation site    Direct interaction pair    Function Annotation

Protein Summary
UniProt/SwissProt ID:FA10_HUMAN
Description:coagulation factor X [Source:HGNC Symbol;Acc:3528]
Location:chr13 q34
Node attribute:gene

Phosphorylation site
PositionPhosphoPeptideCatalytic kinaseSource
Y384MLEVPyVDRNSTrypsinPhosphoSitePlus

Dephosphorylation site
FA10_HUMAN do not have dephosphorylation site.

Mutation site
Ensembl IDVariationSourceCancer namePubmed
ENSP00000364709R387HCOSMICPancreatic Cancer

Differential expressed protein
Ensembl IDCancer nameDesignSampleChangeRatioPubmed
ENSP00000364709Pancreatic CancerNormal vs. CancertissueDown2.816212428
ENSP00000364709hepatitis C virusNormal vs. Cancercell lineDown17928924
ENSP00000364709breast ductal carcinomaNormal vs. CancertissueDown19624269

Hyperphosphorylation site
FA10_HUMAN do not have hyperphosphorylation site.

Direct Interaction Pair
SourceTargetRelationshipResource
HNF4A_HUMANFA10_HUMANTF -> target geneTRANSFAC
SP1_HUMANFA10_HUMANTF -> target geneTRANSFAC

Function Annotation
KEGG Pathway
FA10_HUMAN is not in KEGG pathway.

Gene Ontology
GO IDGO_TermEvidenceOntology
GO:0006508proteolysisTASbiological_process
GO:0004252serine-type endopeptidase activityIEAmolecular_function
GO:0017187peptidyl-glutamic acid carboxylationTASbiological_process
GO:0005515protein bindingIPImolecular_function
GO:0005886plasma membraneTAScellular_component
GO:0007596blood coagulationIEAbiological_process
GO:0031233intrinsic to external side of plasma membraneICcellular_component
GO:0030335positive regulation of cell migrationTASbiological_process
GO:0003824catalytic activityIEAmolecular_function
GO:0016020membraneIEAcellular_component
GO:0005543phospholipid bindingIDAmolecular_function
GO:0043687post-translational protein modificationTASbiological_process
GO:0007596blood coagulationICbiological_process
GO:0005576extracellular regionNAScellular_component
GO:0043231intracellular membrane-bounded organelleIEAcellular_component
GO:0051897positive regulation of protein kinase B signaling IDAbiological_process
GO:0005788endoplasmic reticulum lumenTAScellular_component
GO:0004252serine-type endopeptidase activityIDAmolecular_function
GO:0005796Golgi lumenTAScellular_component
GO:0007598blood coagulation, extrinsic pathwayTASbiological_process
GO:0007597blood coagulation, intrinsic pathwayTASbiological_process
GO:0005509calcium ion bindingIEAmolecular_function
GO:0044267cellular protein metabolic processTASbiological_process


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