Protein information
  Protein summary    Phosphorylation site    Dephosphorylation site    Mutation site
  Differential expressed protein    Hyperphosphorylation site    Direct interaction pair    Function Annotation

Protein Summary
UniProt/SwissProt ID:ETV1_HUMAN
Description:ets variant 1 [Source:HGNC Symbol;Acc:3490]
Location:chr7 p21.2
Node attribute:substrate

Phosphorylation site
PositionPhosphoPeptideCatalytic kinaseSource
S216YQRQMsEPNIPPRKACAHPRD
S334YQRRGsLQLWQPKACaRegPhos
S334YQRRGsLQLWQPRKACAHPRD
S191FRRQLsEPCNSPRKACAHPRD
S334YQRRGsLQLWQRSK3RegPhos
S334YQRRGsLQLWQRSK1RegPhos
T139PSNPPtPSSTPHPRD; RegPhos
T139PSNPPtPSSTPETS_PEA3_NPhosphoSitePlus
S191FRRQLsEPCNSPKACaRegPhos
S191FRRQLsEPCNSRSK-1phosphoELM
S191FRRQLsEPCNSMAPKAPK2HPRD; RegPhos
T143PTPSStPVSPLHPRD; RegPhos
S334YQRRGsLQLWQMSK1RegPhos
S216YQRQMsEPNIPMAPKAPK2HPRD; RegPhos
S216YQRQMsEPNIPRSK-1phosphoELM
S146SSTPVsPLHHAETS_PEA3_NPhosphoSitePlus
S216YQRQMsEPNIPPKACaRegPhos
S216YQRQMsEPNIPRPS6KA1HPRD
S216YQRQMsEPNIPRPS6KA5HPRD
T143PTPSStPVSPLETS_PEA3_NPhosphoSitePlus
Y5_MDGFyDQQVPETS_PEA3_NPhosphoSitePlus
S191FRRQLsEPCNSHPRD; RegPhos
S191FRRQLsEPCNSETS_PEA3_NPhosphoSitePlus
S146SSTPVsPLHHAHPRD; RegPhos
S334YQRRGsLQLWQRSK-1phosphoELM
S216YQRQMsEPNIPHPRD; RegPhos
S216YQRQMsEPNIPMSK1RegPhos
S94KKEPHsPCSEIETS_PEA3_NPhosphoSitePlus
S216YQRQMsEPNIPETS_PEA3_NPhosphoSitePlus
S334YQRRGsLQLWQRPS6KA5HPRD
S334YQRRGsLQLWQRPS6KA1HPRD
S191FRRQLsEPCNSRSK3RegPhos
S191FRRQLsEPCNSMSK1RegPhos
S191FRRQLsEPCNSRPS6KA5HPRD
S191FRRQLsEPCNSRPS6KA1HPRD
S334YQRRGsLQLWQEtsPhosphoSitePlus
S216YQRQMsEPNIPRSK1RegPhos
S216YQRQMsEPNIPRSK3RegPhos
S191FRRQLsEPCNSRSK1RegPhos

Dephosphorylation site
ETV1_HUMAN do not have dephosphorylation site.

Mutation site
Ensembl IDVariationSourceCancer namePubmed
ENSP00000385551P234SCOSMICOvarian Cancer21720365
ENSP00000385551R331PCOSMICHead and Neck Cancer21798893
ENSP00000405327S141YCOSMICLung Cancer20668451
ENSP00000385551F222LCOSMICCentral Nervous System Neoplasms18772396
ENSP00000385551L79MCOSMICLung Cancer
ENSP00000405327L79MCOSMICLung Cancer
ENSP00000385551S141YCOSMICLung Cancer20668451
ENSP00000405327F222LCOSMICCentral Nervous System Neoplasms18772396
ENSP00000405327P234SCOSMICOvarian Cancer21720365
ENSP00000405327R331PCOSMICHead and Neck Cancer21798893

Differential expressed protein
ETV1_HUMAN is not differential expressed protein.

Hyperphosphorylation site
ETV1_HUMAN do not have hyperphosphorylation site.

Direct Interaction Pair
SourceTargetRelationshipResource
ZAGL2_HUMANETV1_HUMANkinase -> substrateRegPhos
KS6A1_HUMANETV1_HUMANkinase -> substrateRegPhos; Robert H Newman (2013)
MAPK2_HUMANETV1_HUMANkinase -> substrateRegPhos
KS6A2_HUMANETV1_HUMANkinase -> substrateRegPhos
MK08_HUMANETV1_HUMANkinase -> substrateRobert H Newman (2013)
KS6A5_HUMANETV1_HUMANkinase -> substrateRegPhos
KPCA_HUMANETV1_HUMANkinase -> substrateHPRD

Function Annotation
KEGG Pathway
KEGG IDPathway
hsa05202Transcriptional misregulation in cancer

Gene Ontology
GO IDGO_TermEvidenceOntology
GO:0006355regulation of transcription, DNA-dependentIEAbiological_process
GO:0003700sequence-specific DNA binding transcription factorIEAmolecular_function
GO:0007517muscle organ developmentIEAbiological_process
GO:0005634nucleusIEAcellular_component
GO:0045893positive regulation of transcription, DNA-dependenIEAbiological_process
GO:0007638mechanosensory behaviorIEAbiological_process
GO:0007411axon guidanceIEAbiological_process
GO:0005515protein bindingIPImolecular_function
GO:0048935peripheral nervous system neuron developmentTASbiological_process
GO:0043565sequence-specific DNA bindingIEAmolecular_function
GO:0006366transcription from RNA polymerase II promoterTASbiological_process


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