| UniProt/SwissProt ID: | ERG_HUMAN |
| Description: | v-ets erythroblastosis virus E26 oncogene homolog (avian) [Source:HGNC Symbol;Acc:3446] |
| Location: | chr21 q22.2 |
| Node attribute: | TF |
| Phosphorylation site |
| Position | PhosphoPeptide | Catalytic kinase | Source |
|---|---|---|---|
| S93 | SPDECsVAKGG | HPRD; SysPTM | |
| S86 | SPDECsVAKGG | HPRD | |
| S85 | SQVNGsRNSPD | phosphoELM | |
| Dephosphorylation site |
| ERG_HUMAN do not have dephosphorylation site. |
| Mutation site |
| Ensembl ID | Variation | Source | Cancer name | Pubmed |
|---|---|---|---|---|
| ENSP00000288319 | R370L | Ding2008, BIOMART | Lung Cancer | 18948947, 21930507, 21930502 | ENSP00000288319 | Q310K | Ding2008, BIOMART | Lung Cancer | 18948947, 21930507, 21930502 |
| Differential expressed protein |
| ERG_HUMAN is not differential expressed protein. |
| Hyperphosphorylation site |
| ERG_HUMAN do not have hyperphosphorylation site. |
| Direct Interaction Pair |
| Source | Target | Relationship | Resource |
|---|---|---|---|
| ERG_HUMAN | NOS3_HUMAN | TF -> target gene | TRANSFAC |
| Function Annotation |
| KEGG Pathway |
| ERG_HUMAN is not in KEGG pathway. |
| Gene Ontology |
| GO ID | GO_Term | Evidence | Ontology |
|---|---|---|---|
| GO:0005634 | nucleus | IEA | cellular_component |
| GO:0004871 | signal transducer activity | TAS | molecular_function |
| GO:0007275 | multicellular organismal development | TAS | biological_process |
| GO:0006355 | regulation of transcription, DNA-dependent | IEA | biological_process |
| GO:0005515 | protein binding | IEA | molecular_function |
| GO:0043565 | sequence-specific DNA binding | IEA | molecular_function |
| GO:0003700 | sequence-specific DNA binding transcription factor | IEA | molecular_function |
| GO:0005737 | cytoplasm | IEA | cellular_component |
| GO:0007165 | signal transduction | TAS | biological_process |
| GO:0006351 | transcription, DNA-dependent | IEA | biological_process |
| GO:0006468 | protein phosphorylation | TAS | biological_process |
| GO:0008283 | cell proliferation | TAS | biological_process |
| GO:0005515 | protein binding | IPI | molecular_function |
| GO:0030529 | ribonucleoprotein complex | IDA | cellular_component |
| GO:0003677 | DNA binding | TAS | molecular_function |