Protein information
  Protein summary    Phosphorylation site    Dephosphorylation site    Mutation site
  Differential expressed protein    Hyperphosphorylation site    Direct interaction pair    Function Annotation

Protein Summary
UniProt/SwissProt ID:EI2BA_HUMAN
Description:eukaryotic translation initiation factor 2B, subunit 1 alpha, 26kDa [Source:HGNC Symbol;Acc:3257]
Location:chr12 q24.31
Node attribute:substrate

Phosphorylation site
PositionPhosphoPeptideCatalytic kinaseSource
S107RRISLsRNKIAIF-2BPhosphoSitePlus
S105FLRRIsLSRNKHPRD
Y83LASLEySDYSKIF-2BPhosphoSitePlus
S107RRISLsRNKIAHPRD
Y130ILTHAySRVVLIF-2BPhosphoSitePlus
S105FLRRIsLSRNKIF-2BPhosphoSitePlus
T29VAAIRtLLEFLIF-2BPhosphoSitePlus

Dephosphorylation site
EI2BA_HUMAN do not have dephosphorylation site.

Mutation site
EI2BA_HUMAN do not have mutation site.

Differential expressed protein
EI2BA_HUMAN is not differential expressed protein.

Hyperphosphorylation site
EI2BA_HUMAN do not have hyperphosphorylation site.

Direct Interaction Pair
SourceTargetRelationshipResource
CSK21_HUMANEI2BA_HUMANkinase -> substrateRobert H Newman (2013)

Function Annotation
KEGG Pathway
EI2BA_HUMAN is not in KEGG pathway.

Gene Ontology
GO IDGO_TermEvidenceOntology
GO:0006446regulation of translational initiationIBAbiological_process
GO:0006417regulation of translationIEAbiological_process
GO:0005515protein bindingIPImolecular_function
GO:0009408response to heatISSbiological_process
GO:0005085guanyl-nucleotide exchange factor activityIDAmolecular_function
GO:0043434response to peptide hormone stimulusIEAbiological_process
GO:0014003oligodendrocyte developmentIMPbiological_process
GO:0005886plasma membraneIDAcellular_component
GO:0006412translationTASbiological_process
GO:0019003GDP bindingIEAmolecular_function
GO:0009749response to glucose stimulusISSbiological_process
GO:0005515protein bindingIEAmolecular_function
GO:0005829cytosolTAScellular_component
GO:0016020membraneIDAcellular_component
GO:0032057negative regulation of translational initiation inIEAbiological_process
GO:0044237cellular metabolic processIEAbiological_process
GO:0005737cytoplasmIDAcellular_component
GO:0006413translational initiationIDAbiological_process
GO:0030234enzyme regulator activityIEAmolecular_function
GO:0051716cellular response to stimulusIDAbiological_process
GO:0009749response to glucose stimulusIEAbiological_process
GO:0006412translationIEAbiological_process
GO:0050790regulation of catalytic activityIEAbiological_process
GO:0005851eukaryotic translation initiation factor 2B compleIDAcellular_component
GO:0003743translation initiation factor activityIDAmolecular_function
GO:0010467gene expressionTASbiological_process
GO:0009408response to heatIEAbiological_process
GO:0005525GTP bindingIEAmolecular_function
GO:0044267cellular protein metabolic processTASbiological_process
GO:0043434response to peptide hormone stimulusISSbiological_process


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