| UniProt/SwissProt ID: | EDF1_HUMAN |
| Description: | endothelial differentiation-related factor 1 [Source:HGNC Symbol;Acc:3164] |
| Location: | chr9 q34.3 |
| Node attribute: | substrate |
| Phosphorylation site |
| Position | PhosphoPeptide | Catalytic kinase | Source |
|---|---|---|---|
| S111 | IADYEsGRAIP | HTH_3 | PhosphoSitePlus |
| T91 | QSKGLtQKDLA | PRKCA | HPRD |
| T74 | HHDRVtLEVGK | PhosphoSitePlus; HPRD | |
| S53 | QNKQHsITKNT | PhosphoSitePlus; HPRD | |
| Y109 | QVIADyESGRA | HTH_3 | PhosphoSitePlus |
| S4 | WDTV | HPRD | |
| Dephosphorylation site |
| EDF1_HUMAN do not have dephosphorylation site. |
| Mutation site |
| EDF1_HUMAN do not have mutation site. |
| Differential expressed protein |
| EDF1_HUMAN is not differential expressed protein. |
| Hyperphosphorylation site |
| EDF1_HUMAN do not have hyperphosphorylation site. |
| Direct Interaction Pair |
| Source | Target | Relationship | Resource |
|---|---|---|---|
| KPCA_HUMAN | EDF1_HUMAN | kinase -> substrate | HPRD |
| MK08_HUMAN | EDF1_HUMAN | kinase -> substrate | Robert H Newman (2013) |
| Function Annotation |
| KEGG Pathway |
| EDF1_HUMAN is not in KEGG pathway. |
| Gene Ontology |
| GO ID | GO_Term | Evidence | Ontology |
|---|---|---|---|
| GO:0006351 | transcription, DNA-dependent | IEA | biological_process |
| GO:0005669 | transcription factor TFIID complex | IDA | cellular_component |
| GO:0043565 | sequence-specific DNA binding | IEA | molecular_function |
| GO:0045893 | positive regulation of transcription, DNA-dependen | TAS | biological_process |
| GO:0006355 | regulation of transcription, DNA-dependent | TAS | biological_process |
| GO:0005737 | cytoplasm | IDA | cellular_component |
| GO:0005634 | nucleus | IDA | cellular_component |
| GO:0005622 | intracellular | TAS | cellular_component |
| GO:0003713 | transcription coactivator activity | IMP | molecular_function |
| GO:0003677 | DNA binding | IEA | molecular_function |
| GO:0007275 | multicellular organismal development | IEA | biological_process |
| GO:0043388 | positive regulation of DNA binding | IDA | biological_process |
| GO:0045446 | endothelial cell differentiation | TAS | biological_process |
| GO:0019216 | regulation of lipid metabolic process | TAS | biological_process |
| GO:0005516 | calmodulin binding | IEA | molecular_function |
| GO:0005730 | nucleolus | IDA | cellular_component |
| GO:0005515 | protein binding | IPI | molecular_function |