Protein information
  Protein summary    Phosphorylation site    Dephosphorylation site    Mutation site
  Differential expressed protein    Hyperphosphorylation site    Direct interaction pair    Function Annotation

Protein Summary
UniProt/SwissProt ID:EDAR_HUMAN
Description:ectodysplasin A receptor [Source:HGNC Symbol;Acc:2895]
Location:chr2 q12.3
Node attribute:receptor; PPI(target)

Phosphorylation site
PositionPhosphoPeptideCatalytic kinaseSource
S357CLEKTsRMLSSPhosphoSitePlus
S366SSTYNsEKAVVPhosphoSitePlus
Y364MLSSTyNSEKAPhosphoSitePlus
S153CVGATsGASANPhosphoSitePlus
S324SAGIQsRRKKIHPRD; phosphoELM
S361TSRMLsSTYNSPhosphoSitePlus
S407STAGYsIPELLDeathPhosphoSitePlus
T363RMLSStYNSEKPhosphoSitePlus

Dephosphorylation site
EDAR_HUMAN do not have dephosphorylation site.

Mutation site
Ensembl IDVariationSourceCancer namePubmed
ENSP00000258443R98QCOSMICMelanoma21499247

Differential expressed protein
EDAR_HUMAN is not differential expressed protein.

Hyperphosphorylation site
EDAR_HUMAN do not have hyperphosphorylation site.

Direct Interaction Pair
SourceTargetRelationshipResource
EDA_HUMANEDAR_HUMANligand -> receptorHPMR
EDA_HUMANEDAR_HUMANotherKEGG

Function Annotation
KEGG Pathway
KEGG IDPathway
hsa04060Cytokine-cytokine receptor interaction

Gene Ontology
GO IDGO_TermEvidenceOntology
GO:0007165signal transductionIEAbiological_process
GO:0008544epidermis developmentTASbiological_process
GO:0030154cell differentiationIEAbiological_process
GO:0005886plasma membraneIEAcellular_component
GO:0043473pigmentationIEAbiological_process
GO:0042346positive regulation of NF-kappaB import into nucleIEAbiological_process
GO:0016021integral to membraneNAScellular_component
GO:0042475odontogenesis of dentin-containing toothIEAbiological_process
GO:0005515protein bindingIPImolecular_function
GO:0006915apoptotic processIEAbiological_process
GO:0045177apical part of cellIEAcellular_component
GO:0001942hair follicle developmentIEAbiological_process
GO:0060662salivary gland cavitationIEAbiological_process
GO:0004888transmembrane signaling receptor activityNASmolecular_function
GO:0004872receptor activityIDAmolecular_function


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