Protein information
  Protein summary    Phosphorylation site    Dephosphorylation site    Mutation site
  Differential expressed protein    Hyperphosphorylation site    Direct interaction pair    Function Annotation

Protein Summary
UniProt/SwissProt ID:DEFI6_HUMAN
Description:differentially expressed in FDCP 6 homolog (mouse) [Source:HGNC Symbol;Acc:2760]
Location:chr6 p21.31
Node attribute:substrate

Phosphorylation site
PositionPhosphoPeptideCatalytic kinaseSource
S566PVTSSsFSGFQPhosphoSitePlus
Y210AIHEVyQELIQLCKHPRD
S606NEQQKsLNGGDPhosphoSitePlus
Y210AIHEVyQELIQPhosphoSitePlus
T538LRQAStNVKHWPhosphoSitePlus
T595SQGNRtPSPNSPhosphoSitePlus
S537KLRQAsTNVKHPhosphoSitePlus
Y144PDEVEyLLKKVPhosphoSitePlus
S600TPSPNsNEQQKPhosphoSitePlus
S580LAHRDsSLKRLPhosphoSitePlus
S618APAPAsTPQEDPhosphoSitePlus
Y222VLKQGyLWKRGPHPhosphoSitePlus
S590LTRWGsQGNRTPhosphoSitePlus
S597GNRTPsPNSNEPhosphoSitePlus
S581AHRDSsLKRLTPhosphoSitePlus
T619PAPAStPQEDKPhosphoSitePlus
S564KRPVTsSSFSGPhosphoSitePlus
T563DKRPVtSSSFSPhosphoSitePlus

Dephosphorylation site
DEFI6_HUMAN do not have dephosphorylation site.

Mutation site
Ensembl IDVariationSourceCancer namePubmed
ENSP00000319831R274CCOSMICHead and Neck Cancer21798893

Differential expressed protein
DEFI6_HUMAN is not differential expressed protein.

Hyperphosphorylation site
DEFI6_HUMAN do not have hyperphosphorylation site.

Direct Interaction Pair
SourceTargetRelationshipResource
LCK_HUMANDEFI6_HUMANkinase -> substrateHPRD

Function Annotation
KEGG Pathway
DEFI6_HUMAN is not in KEGG pathway.

Gene Ontology
GO IDGO_TermEvidenceOntology
GO:0005737cytoplasmIEAcellular_component
GO:0005543phospholipid bindingIEAmolecular_function
GO:0005515protein bindingIEAmolecular_function
GO:0005886plasma membraneIEAcellular_component
GO:0005634nucleusIDAcellular_component


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