Protein information
  Protein summary    Phosphorylation site    Dephosphorylation site    Mutation site
  Differential expressed protein    Hyperphosphorylation site    Direct interaction pair    Function Annotation

Protein Summary
UniProt/SwissProt ID:DDX6_HUMAN
Description:DEAD (Asp-Glu-Ala-Asp) box helicase 6 [Source:HGNC Symbol;Acc:2747]
Location:chr11 q23.3
Node attribute:substrate

Phosphorylation site
PositionPhosphoPeptideCatalytic kinaseSource
T439AINLItYDDRFPhosphoSitePlus
T327VHCLNtLFSRLPhosphoSitePlus
S475VAEYHsEPVEDPhosphoSitePlus; HPRD
T36PGGGGtQTQQQPhosphoSitePlus; HPRD; phosphoELM
T199AKVMAtTGGTNDEADPhosphoSitePlus
Y312KGVTQyYAYVTPhosphoSitePlus
Y472SLYVAeYHSEPHPRD
Y440INLITyDDRFNPhosphoSitePlus
T87DLRIKtSDVTSPhosphoSitePlus
Y313GVTQYyAYVTEPhosphoSitePlus
Y473LYVAEyHSEPVPhosphoSitePlus; HPRD
S330LNTLFsRLQINPhosphoSitePlus
T199AKVMAtTGGTNHPRD
Y469IDKSLyVAEYHPhosphoSitePlus
S16IMGLSsQNGQLPhosphoSitePlus
T38GGGTQtQQQMNPhosphoSitePlus

Dephosphorylation site
DDX6_HUMAN do not have dephosphorylation site.

Mutation site
DDX6_HUMAN do not have mutation site.

Differential expressed protein
Ensembl IDCancer nameDesignSampleChangeRatioPubmed
ENSP00000264018Testicular CancerNormal vs. Cancercell lineUp18489135

Hyperphosphorylation site
DDX6_HUMAN do not have hyperphosphorylation site.

Direct Interaction Pair
SourceTargetRelationshipResource
FGFR1_HUMANDDX6_HUMANkinase -> substrateRobert H Newman (2013)

Function Annotation
KEGG Pathway
DDX6_HUMAN is not in KEGG pathway.

Gene Ontology
GO IDGO_TermEvidenceOntology
GO:0033962cytoplasmic mRNA processing body assemblyIDAbiological_process
GO:0005515protein bindingIPImolecular_function
GO:0003724RNA helicase activityTASmolecular_function
GO:0016071mRNA metabolic processTASbiological_process
GO:0000932cytoplasmic mRNA processing bodyIDAcellular_component
GO:0003723RNA bindingIEAmolecular_function
GO:0016442RNA-induced silencing complexIDAcellular_component
GO:0008026ATP-dependent helicase activityIEAmolecular_function
GO:0010494cytoplasmic stress granuleIDAcellular_component
GO:0003676nucleic acid bindingIEAmolecular_function
GO:0005829cytosolTAScellular_component
GO:0005737cytoplasmIEAcellular_component
GO:0005524ATP bindingIEAmolecular_function
GO:0004386helicase activityTASmolecular_function
GO:0010467gene expressionTASbiological_process
GO:0000288nuclear-transcribed mRNA catabolic process, deadenTASbiological_process
GO:0043928exonucleolytic nuclear-transcribed mRNA catabolic TASbiological_process
GO:0016070RNA metabolic processTASbiological_process


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