| UniProt/SwissProt ID: | DDX4_HUMAN |
| Description: | DEAD (Asp-Glu-Ala-Asp) box polypeptide 4 [Source:HGNC Symbol;Acc:18700] |
| Location: | chr5 q11.2 |
| Node attribute: | substrate |
| Phosphorylation site |
| Position | PhosphoPeptide | Catalytic kinase | Source |
|---|---|---|---|
| S139 | RDGNNsEASGP | PhosphoSitePlus | |
| Y133 | SKRGGyRDGNN | PhosphoSitePlus | |
| Y442 | LKQIKyLVLDE | DEAD | PhosphoSitePlus |
| S90 | FGVGKsFGNRG | PhosphoSitePlus | |
| T312 | GYTKLtPVQKY | DEAD | PhosphoSitePlus |
| T37 | DNFNRtPASSS | PhosphoSitePlus | |
| T339 | TGSGKtAAFLL | DEAD | PhosphoSitePlus |
| Dephosphorylation site |
| DDX4_HUMAN do not have dephosphorylation site. |
| Mutation site |
| DDX4_HUMAN do not have mutation site. |
| Differential expressed protein |
| DDX4_HUMAN is not differential expressed protein. |
| Hyperphosphorylation site |
| DDX4_HUMAN do not have hyperphosphorylation site. |
| Direct Interaction Pair |
| Source | Target | Relationship | Resource |
|---|---|---|---|
| WEE1_HUMAN | DDX4_HUMAN | kinase -> substrate | Robert H Newman (2013) |
| KS6A2_HUMAN | DDX4_HUMAN | kinase -> substrate | Robert H Newman (2013) |
| CDK4_HUMAN | DDX4_HUMAN | kinase -> substrate | Robert H Newman (2013) |
| DYRK4_HUMAN | DDX4_HUMAN | kinase -> substrate | Robert H Newman (2013) |
| Function Annotation |
| KEGG Pathway |
| DDX4_HUMAN is not in KEGG pathway. |
| Gene Ontology |
| GO ID | GO_Term | Evidence | Ontology |
|---|---|---|---|
| GO:0005524 | ATP binding | IEA | molecular_function |
| GO:0048471 | perinuclear region of cytoplasm | IEA | cellular_component |
| GO:0044464 | cell part | IEA | cellular_component |
| GO:0008026 | ATP-dependent helicase activity | IEA | molecular_function |
| GO:0007283 | spermatogenesis | IEA | biological_process |
| GO:0005737 | cytoplasm | IDA | cellular_component |
| GO:0000237 | leptotene | IEA | biological_process |
| GO:0032880 | regulation of protein localization | IEA | biological_process |
| GO:0005737 | cytoplasm | IEA | cellular_component |
| GO:0003676 | nucleic acid binding | IEA | molecular_function |
| GO:0071547 | piP-body | ISS | cellular_component |
| GO:0007141 | male meiosis I | IEA | biological_process |
| GO:0071546 | pi-body | ISS | cellular_component |
| GO:0030317 | sperm motility | IMP | biological_process |
| GO:0007275 | multicellular organismal development | IEA | biological_process |
| GO:0004386 | helicase activity | IEA | molecular_function |
| GO:0033391 | chromatoid body | IEA | cellular_component |
| GO:0005634 | nucleus | IEA | cellular_component |
| GO:0030529 | ribonucleoprotein complex | IEA | cellular_component |