| UniProt/SwissProt ID: | DCOR_HUMAN |
| Description: | ornithine decarboxylase 1 [Source:HGNC Symbol;Acc:8109] |
| Location: | chr2 p25.1 |
| Node attribute: | gene |
| Phosphorylation site |
| DCOR_HUMAN do not have phosphorylation site. |
| Dephosphorylation site |
| DCOR_HUMAN do not have dephosphorylation site. |
| Mutation site |
| Ensembl ID | Variation | Source | Cancer name | Pubmed |
|---|---|---|---|---|
| ENSP00000234111 | V128F | COSMIC | Central Nervous System Neoplasms | 21817013 | ENSP00000234111 | D10G | COSMIC | Ovarian Cancer | 21720365 |
| Differential expressed protein |
| Ensembl ID | Cancer name | Design | Sample | Change | Ratio | Pubmed |
|---|---|---|---|---|---|---|
| ENSP00000385333 | Neoplasms by Histologic Type | Treatment (none vs. SB203580 treatment 21 hour) | cell line | Down | 0.64 | 15169874 |
| Hyperphosphorylation site |
| DCOR_HUMAN do not have hyperphosphorylation site. |
| Direct Interaction Pair |
| Source | Target | Relationship | Resource |
|---|---|---|---|
| MYC_HUMAN | DCOR_HUMAN | TF -> target gene | TRANSFAC |
| AP2A_HUMAN | DCOR_HUMAN | TF -> target gene | TRANSFAC |
| MAX_FELCA | DCOR_HUMAN | TF -> target gene | TRANSFAC |
| Function Annotation |
| KEGG Pathway |
| DCOR_HUMAN is not in KEGG pathway. |
| Gene Ontology |
| GO ID | GO_Term | Evidence | Ontology |
|---|---|---|---|
| GO:0005575 | cellular_component | ND | cellular_component |
| GO:0009446 | putrescine biosynthetic process | IEA | biological_process |
| GO:0004586 | ornithine decarboxylase activity | IEA | molecular_function |
| GO:0006521 | regulation of cellular amino acid metabolic proces | TAS | biological_process |
| GO:0006596 | polyamine biosynthetic process | IEA | biological_process |
| GO:0008284 | positive regulation of cell proliferation | IEA | biological_process |
| GO:0001822 | kidney development | IEA | biological_process |
| GO:0044281 | small molecule metabolic process | TAS | biological_process |
| GO:0005829 | cytosol | IEA | cellular_component |
| GO:0034641 | cellular nitrogen compound metabolic process | TAS | biological_process |
| GO:0006595 | polyamine metabolic process | IEA | biological_process |
| GO:0006595 | polyamine metabolic process | TAS | biological_process |
| GO:0009615 | response to virus | IEP | biological_process |
| GO:0033387 | putrescine biosynthetic process from ornithine | IEA | biological_process |
| GO:0003824 | catalytic activity | IEA | molecular_function |