Protein information
  Protein summary    Phosphorylation site    Dephosphorylation site    Mutation site
  Differential expressed protein    Hyperphosphorylation site    Direct interaction pair    Function Annotation

Protein Summary
UniProt/SwissProt ID:DBNL_HUMAN
Description:drebrin-like [Source:HGNC Symbol;Acc:2696]
Location:chr7 p13
Node attribute:substrate

Phosphorylation site
PositionPhosphoPeptideCatalytic kinaseSource
S284PGKLRsPFLQKHPRD
T270ERAMStTSISSUPF0560PhosphoSitePlus
S276TTSISsPQPGKHPRD
T291LQKQLtQPETHUPF0560PhosphoSitePlus; SysPTM
S274STTSIsSPQPGUPF0560PhosphoSitePlus
Y140ASGANySFHKEUPF0560PhosphoSitePlus
T271ERAMStTSISSHPRD
S275TTSISsPQPGKUPF0560PhosphoSitePlus; SysPTM
Y162PVGSVyQKTNAUPF0560PhosphoSitePlus
S269KERAMsTTSISHPRD; phosphoELM; RegPhos
S178RVGKDsFWAKAUPF0560PhosphoSitePlus; SysPTM
S232QGGEAsPQRTWHPRD; phosphoELM; RegPhos; SysPTM
S320EEPAPsTPPCLHPRD
Y344EQETFyEQPPLZAP70HPRD; phosphoELM; RegPhos
Y344EQETFyEQPPLUPF0560PhosphoSitePlus
S283PGKLRsPFLQKUPF0560PhosphoSitePlus; SysPTM
S275STTSIsSPQPGHPRD; SysPTM
S178RVGKDsFWAKAHPRD; phosphoELM; RegPhos; SysPTM
T292LQKQLtQPETHHPRD
S272AMSTTsISSPQUPF0560PhosphoSitePlus
T271RAMSTtSISSPUPF0560PhosphoSitePlus
S136KVAKAsGANYSUPF0560PhosphoSitePlus
S320EEPAPsTPPCLUPF0560PhosphoSitePlus
T165SVYQKtNAVSEUPF0560PhosphoSitePlus
S275TTSISsPQPGKHPRD; phosphoELM; RegPhos; SysPTM
T21YVRVVtEKSPTCofilin_ADFPhosphoSitePlus
S160QAPVGsVYQKTUPF0560PhosphoSitePlus
Y16ALQEAyVRVVTCofilin_ADFPhosphoSitePlus
Y162PVGSVyQKTNAHPRD; phosphoELM; RegPhos
S169KTNAVsEIKRVUPF0560PhosphoSitePlus
Y345EQETFyEQPPLZAP70HPRD
S321EEPAPsTPPCLHPRD
S146SFHKEsGRFQDUPF0560PhosphoSitePlus
S6MAANLsRNGPAPhosphoSitePlus
S283PGKLRsPFLQKHPRD; phosphoELM; RegPhos; SysPTM
T296LTQPEtHFGREHPRD
Y224RREQRyQEQGGUPF0560PhosphoSitePlus
S273AMSTTsISSPQHPRD
Y335EEEAVyEEPPEZAP70HPRD
S274STTSIsSPQPGHPRD
T45IRVAGtGEGGLCofilin_ADFPhosphoSitePlus
S272AMSTTsISSPQHPRD; phosphoELM; RegPhos
S232QGGEAsPQRTWUPF0560PhosphoSitePlus; SysPTM
S270KERAMsTTSISHPRD
S269KERAMsTTSISUPF0560PhosphoSitePlus
Y344EQETFyEQPPLRegPhos
S141SGANYsFHKESUPF0560PhosphoSitePlus
S232QGGEAsPQSRTHPRD; SysPTM
Y334EEEAVyEEPPEZAP70HPRD; phosphoELM; RegPhos
T270ERAMStTSISSHPRD; RegPhos
Y334EEEAVyEEPPERegPhos
T295LTQPEtHFGREHPRD
Y140ASGANySFHKEHPRD
T291LQKQLtQPETHHPRD; phosphoELM; RegPhos; SysPTM
Y334EEEAVyEEPPEUPF0560PhosphoSitePlus

Dephosphorylation site
DBNL_HUMAN do not have dephosphorylation site.

Mutation site
DBNL_HUMAN do not have mutation site.

Differential expressed protein
Ensembl IDCancer nameDesignSampleChangeRatioPubmed
ENSP00000411701Uterine CancerNormal vs. CancertissueUp16051329
ENSP00000411701Uterine CancerNormal vs. CancertissueUp19771267

Hyperphosphorylation site
DBNL_HUMAN do not have hyperphosphorylation site.

Direct Interaction Pair
SourceTargetRelationshipResource
ZAGL2_HUMANDBNL_HUMANkinase -> substrateRegPhos
ZAP70_HUMANDBNL_HUMANkinase -> substrateRegPhos; NetPath; Robert H Newman (2013)

Function Annotation
KEGG Pathway
DBNL_HUMAN is not in KEGG pathway.

Gene Ontology
GO IDGO_TermEvidenceOntology
GO:0016601Rac protein signal transductionIEAbiological_process
GO:0014069postsynaptic densityIEAcellular_component
GO:0005622intracellularIEAcellular_component
GO:0001726ruffleIEAcellular_component
GO:0051015actin filament bindingIEAmolecular_function
GO:0005515protein bindingIEAmolecular_function
GO:0005938cell cortexIEAcellular_component
GO:0008047enzyme activator activityTASmolecular_function
GO:0006921cellular component disassembly involved in executiTASbiological_process
GO:0030425dendriteIEAcellular_component
GO:0007257activation of JUN kinase activityTASbiological_process
GO:0003779actin bindingIEAmolecular_function
GO:0030027lamellipodiumIEAcellular_component
GO:0006897endocytosisIEAbiological_process
GO:0005829cytosolTAScellular_component
GO:0008022protein C-terminus bindingIEAmolecular_function
GO:0005737cytoplasmISScellular_component
GO:0005515protein bindingIPImolecular_function
GO:0006915apoptotic processTASbiological_process
GO:0003779actin bindingISSmolecular_function
GO:0005737cytoplasmIEAcellular_component
GO:0019904protein domain specific bindingIEAmolecular_function


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