| UniProt/SwissProt ID: | DBNL_HUMAN |
| Description: | drebrin-like [Source:HGNC Symbol;Acc:2696] |
| Location: | chr7 p13 |
| Node attribute: | substrate |
| Phosphorylation site |
| Position | PhosphoPeptide | Catalytic kinase | Source |
|---|---|---|---|
| S284 | PGKLRsPFLQK | HPRD | |
| T270 | ERAMStTSISS | UPF0560 | PhosphoSitePlus |
| S276 | TTSISsPQPGK | HPRD | |
| T291 | LQKQLtQPETH | UPF0560 | PhosphoSitePlus; SysPTM |
| S274 | STTSIsSPQPG | UPF0560 | PhosphoSitePlus |
| Y140 | ASGANySFHKE | UPF0560 | PhosphoSitePlus |
| T271 | ERAMStTSISS | HPRD | |
| S275 | TTSISsPQPGK | UPF0560 | PhosphoSitePlus; SysPTM |
| Y162 | PVGSVyQKTNA | UPF0560 | PhosphoSitePlus |
| S269 | KERAMsTTSIS | HPRD; phosphoELM; RegPhos | |
| S178 | RVGKDsFWAKA | UPF0560 | PhosphoSitePlus; SysPTM |
| S232 | QGGEAsPQRTW | HPRD; phosphoELM; RegPhos; SysPTM | |
| S320 | EEPAPsTPPCL | HPRD | |
| Y344 | EQETFyEQPPL | ZAP70 | HPRD; phosphoELM; RegPhos |
| Y344 | EQETFyEQPPL | UPF0560 | PhosphoSitePlus |
| S283 | PGKLRsPFLQK | UPF0560 | PhosphoSitePlus; SysPTM |
| S275 | STTSIsSPQPG | HPRD; SysPTM | |
| S178 | RVGKDsFWAKA | HPRD; phosphoELM; RegPhos; SysPTM | |
| T292 | LQKQLtQPETH | HPRD | |
| S272 | AMSTTsISSPQ | UPF0560 | PhosphoSitePlus |
| T271 | RAMSTtSISSP | UPF0560 | PhosphoSitePlus |
| S136 | KVAKAsGANYS | UPF0560 | PhosphoSitePlus |
| S320 | EEPAPsTPPCL | UPF0560 | PhosphoSitePlus |
| T165 | SVYQKtNAVSE | UPF0560 | PhosphoSitePlus |
| S275 | TTSISsPQPGK | HPRD; phosphoELM; RegPhos; SysPTM | |
| T21 | YVRVVtEKSPT | Cofilin_ADF | PhosphoSitePlus |
| S160 | QAPVGsVYQKT | UPF0560 | PhosphoSitePlus |
| Y16 | ALQEAyVRVVT | Cofilin_ADF | PhosphoSitePlus |
| Y162 | PVGSVyQKTNA | HPRD; phosphoELM; RegPhos | |
| S169 | KTNAVsEIKRV | UPF0560 | PhosphoSitePlus |
| Y345 | EQETFyEQPPL | ZAP70 | HPRD |
| S321 | EEPAPsTPPCL | HPRD | |
| S146 | SFHKEsGRFQD | UPF0560 | PhosphoSitePlus |
| S6 | MAANLsRNGPA | PhosphoSitePlus | |
| S283 | PGKLRsPFLQK | HPRD; phosphoELM; RegPhos; SysPTM | |
| T296 | LTQPEtHFGRE | HPRD | |
| Y224 | RREQRyQEQGG | UPF0560 | PhosphoSitePlus |
| S273 | AMSTTsISSPQ | HPRD | |
| Y335 | EEEAVyEEPPE | ZAP70 | HPRD |
| S274 | STTSIsSPQPG | HPRD | |
| T45 | IRVAGtGEGGL | Cofilin_ADF | PhosphoSitePlus |
| S272 | AMSTTsISSPQ | HPRD; phosphoELM; RegPhos | |
| S232 | QGGEAsPQRTW | UPF0560 | PhosphoSitePlus; SysPTM |
| S270 | KERAMsTTSIS | HPRD | |
| S269 | KERAMsTTSIS | UPF0560 | PhosphoSitePlus |
| Y344 | EQETFyEQPPL | RegPhos | |
| S141 | SGANYsFHKES | UPF0560 | PhosphoSitePlus |
| S232 | QGGEAsPQSRT | HPRD; SysPTM | |
| Y334 | EEEAVyEEPPE | ZAP70 | HPRD; phosphoELM; RegPhos |
| T270 | ERAMStTSISS | HPRD; RegPhos | |
| Y334 | EEEAVyEEPPE | RegPhos | |
| T295 | LTQPEtHFGRE | HPRD | |
| Y140 | ASGANySFHKE | HPRD | |
| T291 | LQKQLtQPETH | HPRD; phosphoELM; RegPhos; SysPTM | |
| Y334 | EEEAVyEEPPE | UPF0560 | PhosphoSitePlus |
| Dephosphorylation site |
| DBNL_HUMAN do not have dephosphorylation site. |
| Mutation site |
| DBNL_HUMAN do not have mutation site. |
| Differential expressed protein |
| Ensembl ID | Cancer name | Design | Sample | Change | Ratio | Pubmed |
|---|---|---|---|---|---|---|
| ENSP00000411701 | Uterine Cancer | Normal vs. Cancer | tissue | Up | 16051329 | ENSP00000411701 | Uterine Cancer | Normal vs. Cancer | tissue | Up | 19771267 |
| Hyperphosphorylation site |
| DBNL_HUMAN do not have hyperphosphorylation site. |
| Direct Interaction Pair |
| Source | Target | Relationship | Resource |
|---|---|---|---|
| ZAGL2_HUMAN | DBNL_HUMAN | kinase -> substrate | RegPhos |
| ZAP70_HUMAN | DBNL_HUMAN | kinase -> substrate | RegPhos; NetPath; Robert H Newman (2013) |
| Function Annotation |
| KEGG Pathway |
| DBNL_HUMAN is not in KEGG pathway. |
| Gene Ontology |
| GO ID | GO_Term | Evidence | Ontology |
|---|---|---|---|
| GO:0016601 | Rac protein signal transduction | IEA | biological_process |
| GO:0014069 | postsynaptic density | IEA | cellular_component |
| GO:0005622 | intracellular | IEA | cellular_component |
| GO:0001726 | ruffle | IEA | cellular_component |
| GO:0051015 | actin filament binding | IEA | molecular_function |
| GO:0005515 | protein binding | IEA | molecular_function |
| GO:0005938 | cell cortex | IEA | cellular_component |
| GO:0008047 | enzyme activator activity | TAS | molecular_function |
| GO:0006921 | cellular component disassembly involved in executi | TAS | biological_process |
| GO:0030425 | dendrite | IEA | cellular_component |
| GO:0007257 | activation of JUN kinase activity | TAS | biological_process |
| GO:0003779 | actin binding | IEA | molecular_function |
| GO:0030027 | lamellipodium | IEA | cellular_component |
| GO:0006897 | endocytosis | IEA | biological_process |
| GO:0005829 | cytosol | TAS | cellular_component |
| GO:0008022 | protein C-terminus binding | IEA | molecular_function |
| GO:0005737 | cytoplasm | ISS | cellular_component |
| GO:0005515 | protein binding | IPI | molecular_function |
| GO:0006915 | apoptotic process | TAS | biological_process |
| GO:0003779 | actin binding | ISS | molecular_function |
| GO:0005737 | cytoplasm | IEA | cellular_component |
| GO:0019904 | protein domain specific binding | IEA | molecular_function |