Protein information
  Protein summary    Phosphorylation site    Dephosphorylation site    Mutation site
  Differential expressed protein    Hyperphosphorylation site    Direct interaction pair    Function Annotation

Protein Summary
UniProt/SwissProt ID:DAAM1_HUMAN
Description:dishevelled associated activator of morphogenesis 1 [Source:HGNC Symbol;Acc:18142]
Location:chr14 q23.1
Node attribute:PPI(target)

Phosphorylation site
PositionPhosphoPeptideCatalytic kinaseSource
Y833QRGNAyGFKISFH2PhosphoSitePlus
T255YASERtRFQTLDrf_FH3PhosphoSitePlus
T1061NRKRItNQMTDPhosphoSitePlus
Y247QAMLHyQKYASDrf_FH3PhosphoSitePlus
S799VEAIRsGSEEVFH2PhosphoSitePlus
T259RTRFQtLINDLDrf_FH3PhosphoSitePlus
T425QDPDStPLENFDrf_FH3PhosphoSitePlus
S34RLRNDsNFALQPhosphoSitePlus
Y401GNTVQyWLLLDDrf_FH3PhosphoSitePlus
S801AIRSGsEEVFRFH2PhosphoSitePlus
S678DDTLSsKLKVKHPRD

Dephosphorylation site
DAAM1_HUMAN do not have dephosphorylation site.

Mutation site
Ensembl IDVariationSourceCancer namePubmed
ENSP00000247170A832GTCGAOvarian Cancer21720365, 18772890
ENSP00000247170R766*COSMICHead and Neck Cancer21798893
ENSP00000247170P604LCOSMICSkin Cancer21984974
ENSP00000378557E763DCOSMICHead and Neck Cancer21798893
ENSP00000354162E867QBIOMARTBreast Cancer21930507, 21930502
ENSP00000378557P604LCOSMICSkin Cancer21984974
ENSP00000378557R766*COSMICHead and Neck Cancer21798893
ENSP00000378557E877QBIOMARTBreast Cancer21930507, 21930502
ENSP00000247170E763DCOSMICHead and Neck Cancer21798893
ENSP00000247170E877QBIOMARTBreast Cancer21930507, 21930502
ENSP00000247170E750KCOSMICHead and Neck Cancer21798893
ENSP00000247170E492QCOSMICHead and Neck Cancer21798893
ENSP00000247170A832GCOSMICOvarian Cancer21720365
ENSP00000378557E492QCOSMICHead and Neck Cancer21798893
ENSP00000378557A832GTCGAOvarian Cancer21720365, 18772890
ENSP00000378557E750KCOSMICHead and Neck Cancer21798893
ENSP00000378557A832GCOSMICOvarian Cancer21720365

Differential expressed protein
Ensembl IDCancer nameDesignSampleChangeRatioPubmed
ENSP00000247170Testicular CancerNormal vs. Cancercell lineDown18489135

Hyperphosphorylation site
DAAM1_HUMAN do not have hyperphosphorylation site.

Direct Interaction Pair
SourceTargetRelationshipResource
RHOA_HUMANDAAM1_HUMANotherKEGG

Function Annotation
KEGG Pathway
KEGG IDPathway
hsa04310Wnt signaling pathway

Gene Ontology
GO IDGO_TermEvidenceOntology
GO:0001725stress fiberIEAcellular_component
GO:0005515protein bindingIEAmolecular_function
GO:0001725stress fiberIDAcellular_component
GO:0005886plasma membraneIDAcellular_component
GO:0000166nucleotide bindingIEAmolecular_function
GO:0030036actin cytoskeleton organizationIEAbiological_process
GO:0005737cytoplasmIDAcellular_component
GO:0005515protein bindingIPImolecular_function
GO:0017048Rho GTPase bindingIEAmolecular_function
GO:0016043cellular component organizationIEAbiological_process
GO:0005488bindingIEAmolecular_function
GO:0003779actin bindingIEAmolecular_function


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