| UniProt/SwissProt ID: | CYH1_HUMAN |
| Description: | cytohesin 1 [Source:HGNC Symbol;Acc:9501] |
| Location: | chr17 q25.3 |
| Node attribute: | substrate |
| Phosphorylation site |
| Position | PhosphoPeptide | Catalytic kinase | Source |
|---|---|---|---|
| T395 | KKVSStKRH | PKC_group | RegPhos |
| Y382 | SRDPFyEMLAA | PhosphoSitePlus | |
| T395 | KKVSStKRH__ | PhosphoSitePlus | |
| T395 | KKVSStKRH | PKCd | RegPhos |
| S394 | KKKVSsTKRH | PKCd | RegPhos |
| S393 | RKKKVsSTKRH | PKCd | RegPhos |
| T395 | KKVSStK | PRKCD | HPRD |
| T394 | KKVSStK | PRKCD | HPRD |
| S394 | KKKVSsTKRH_ | PhosphoSitePlus | |
| S394 | KKKVSsTKRH | PKC_group | RegPhos |
| T395 | KKVSStK | PKC_group | phosphoELM |
| S394 | KKKVSsTK | PKC_group | phosphoELM |
| S394 | KKKVSsTK | PRKCD | HPRD |
| S393 | KKKVSsTK | PRKCD | HPRD |
| Dephosphorylation site |
| CYH1_HUMAN do not have dephosphorylation site. |
| Mutation site |
| Ensembl ID | Variation | Source | Cancer name | Pubmed |
|---|---|---|---|---|
| ENSP00000354398 | R219Q | COSMIC | Head and Neck Cancer | 21798893 | ENSP00000354398 | A386T | COSMIC | Ovarian Cancer | 21720365 |
| Differential expressed protein |
| CYH1_HUMAN is not differential expressed protein. |
| Hyperphosphorylation site |
| CYH1_HUMAN do not have hyperphosphorylation site. |
| Direct Interaction Pair |
| Source | Target | Relationship | Resource |
|---|---|---|---|
| KPCD_HUMAN | CYH1_HUMAN | kinase -> substrate | HPRD |
| Function Annotation |
| KEGG Pathway |
| CYH1_HUMAN is not in KEGG pathway. |
| Gene Ontology |
| GO ID | GO_Term | Evidence | Ontology |
|---|---|---|---|
| GO:0005622 | intracellular | IEA | cellular_component |
| GO:0005086 | ARF guanyl-nucleotide exchange factor activity | IEA | molecular_function |
| GO:0005515 | protein binding | IEA | molecular_function |
| GO:0090162 | establishment of epithelial cell polarity | IEA | biological_process |
| GO:0005923 | tight junction | IEA | cellular_component |
| GO:0030155 | regulation of cell adhesion | IDA | biological_process |
| GO:0032012 | regulation of ARF protein signal transduction | IEA | biological_process |
| GO:0005886 | plasma membrane | IDA | cellular_component |
| GO:0005737 | cytoplasm | IDA | cellular_component |
| GO:0005543 | phospholipid binding | IEA | molecular_function |
| GO:0005515 | protein binding | IPI | molecular_function |