Protein information
  Protein summary    Phosphorylation site    Dephosphorylation site    Mutation site
  Differential expressed protein    Hyperphosphorylation site    Direct interaction pair    Function Annotation

Protein Summary
UniProt/SwissProt ID:CTGF_HUMAN
Description:connective tissue growth factor [Source:HGNC Symbol;Acc:2500]
Location:chr6 q23.2
Node attribute:ligand

Phosphorylation site
PositionPhosphoPeptideCatalytic kinaseSource
S118GESFQsSCKYQVWCPhosphoSitePlus
Y122QSSCKyQCTCLVWCPhosphoSitePlus
Y340IFESLyYRKMYCys_knotPhosphoSitePlus

Dephosphorylation site
CTGF_HUMAN do not have dephosphorylation site.

Mutation site
CTGF_HUMAN do not have mutation site.

Differential expressed protein
Ensembl IDCancer nameDesignSampleChangeRatioPubmed
ENSP00000356954Pancreatic CancerNormal vs. CancertissueDown0.0516215274

Hyperphosphorylation site
CTGF_HUMAN do not have hyperphosphorylation site.

Direct Interaction Pair
SourceTargetRelationshipResource
CTGF_HUMANLRP6_HUMANligand -> receptorHPMR

Function Annotation
KEGG Pathway
CTGF_HUMAN is not in KEGG pathway.

Gene Ontology
GO IDGO_TermEvidenceOntology
GO:0044281small molecule metabolic processTASbiological_process
GO:0070542response to fatty acidIEAbiological_process
GO:0008284positive regulation of cell proliferationIEAbiological_process
GO:0010628positive regulation of gene expressionIEAbiological_process
GO:0001502cartilage condensationIEAbiological_process
GO:0043231intracellular membrane-bounded organelleIDAcellular_component
GO:0070278extracellular matrix constituent secretionIEAbiological_process
GO:0005178integrin bindingIEAmolecular_function
GO:0005829cytosolIEAcellular_component
GO:0035988chondrocyte proliferationIEAbiological_process
GO:0005578proteinaceous extracellular matrixIEAcellular_component
GO:0030154cell differentiationIEAbiological_process
GO:0001934positive regulation of protein phosphorylationIEAbiological_process
GO:0005615extracellular spaceIEAcellular_component
GO:0030324lung developmentIEAbiological_process
GO:0005938cell cortexIEAcellular_component
GO:0010467gene expressionTASbiological_process
GO:0010942positive regulation of cell deathIEAbiological_process
GO:0032330regulation of chondrocyte differentiationIEAbiological_process
GO:0005794Golgi apparatusIDAcellular_component
GO:0005576extracellular regionTAScellular_component
GO:0070374positive regulation of ERK1 and ERK2 cascadeIDAbiological_process
GO:0005576extracellular regionIEAcellular_component
GO:0060401cytosolic calcium ion transportIEAbiological_process
GO:0043280positive regulation of cysteine-type endopeptidaseIEAbiological_process
GO:0014070response to organic cyclic compoundIEAbiological_process
GO:0034059response to anoxiaIEAbiological_process
GO:0051385response to mineralocorticoid stimulusIEAbiological_process
GO:0032355response to estradiol stimulusIEAbiological_process
GO:0008544epidermis developmentTASbiological_process
GO:0035556intracellular signal transductionIEAbiological_process
GO:0009749response to glucose stimulusIEAbiological_process
GO:0005886plasma membraneTAScellular_component
GO:0001525angiogenesisIEAbiological_process
GO:0060452positive regulation of cardiac muscle contractionIEAbiological_process
GO:0043434response to peptide hormone stimulusIEAbiological_process
GO:0006260DNA replicationIEAbiological_process
GO:0005515protein bindingIEAmolecular_function
GO:0045597positive regulation of cell differentiationIDAbiological_process
GO:0010260organ senescenceIEAbiological_process
GO:0008201heparin bindingIEAmolecular_function
GO:0010629negative regulation of gene expressionIEAbiological_process
GO:0007160cell-matrix adhesionIEAbiological_process
GO:0009611response to woundingTASbiological_process
GO:0001558regulation of cell growthIEAbiological_process
GO:0032967positive regulation of collagen biosynthetic proceIEAbiological_process
GO:0070318positive regulation of G0 to G1 transitionIEAbiological_process
GO:0051496positive regulation of stress fiber assemblyIDAbiological_process
GO:0007229integrin-mediated signaling pathwayIEAbiological_process
GO:0008543fibroblast growth factor receptor signaling pathwaIEAbiological_process
GO:0046330positive regulation of JNK cascadeIDAbiological_process
GO:0005801cis-Golgi networkIEAcellular_component
GO:0072593reactive oxygen species metabolic processIEAbiological_process
GO:0048471perinuclear region of cytoplasmIEAcellular_component
GO:0050867positive regulation of cell activationIEAbiological_process
GO:0043200response to amino acid stimulusIEAbiological_process
GO:0001503ossificationIEAbiological_process
GO:0005520insulin-like growth factor bindingIEAmolecular_function
GO:0016477cell migrationIEAbiological_process
GO:0044255cellular lipid metabolic processTASbiological_process
GO:0006367transcription initiation from RNA polymerase II prTASbiological_process
GO:0001968fibronectin bindingIEAmolecular_function
GO:0008083growth factor activityIEAmolecular_function