Protein information
  Protein summary    Phosphorylation site    Dephosphorylation site    Mutation site
  Differential expressed protein    Hyperphosphorylation site    Direct interaction pair    Function Annotation

Protein Summary
UniProt/SwissProt ID:CRIP2_HUMAN
Description:cysteine-rich protein 2 [Source:HGNC Symbol;Acc:2361]
Location:chr14 q32.33
Node attribute:substrate

Phosphorylation site
PositionPhosphoPeptideCatalytic kinaseSource
Y196GAVGSyIYDRDPhosphoSitePlus; HPRD; SysPTM
Y77AGSYIyEKPLAPhosphoSitePlus; HPRD; phosphoELM
T117RASSVtTFTGEPhosphoSitePlus; HPRD; phosphoELM
T88EGPQVtGPIEVPhosphoSitePlus
S115PSRASsVTTFTPhosphoSitePlus; HPRD; phosphoELM
Y198VGSYIyDRDPEPhosphoSitePlus; HPRD; SysPTM
S111PPKGPsRASSVPhosphoSitePlus
Y13CDKTVyFAEKVzf-DNA_Pol; LIMPhosphoSitePlus
Y134CSKKVyFAEKVzf-DNA_Pol; LIMPhosphoSitePlus
S104EERKAsGPPKGPKG1RegPhos
Y75GGAGSyIYEKPPhosphoSitePlus
S104EERKAsGPPKGPRKG1HPRD
S195TGAVGsYIYDRPhosphoSitePlus
S74IGGAGsYIYEKPhosphoSitePlus
S104EERKAsGPPKGPKG1/cGK-IphosphoELM
S114GPSRAsSVTTFPhosphoSitePlus; HPRD

Dephosphorylation site
CRIP2_HUMAN do not have dephosphorylation site.

Mutation site
CRIP2_HUMAN do not have mutation site.

Differential expressed protein
Ensembl IDCancer nameDesignSampleChangeRatioPubmed
ENSP00000328521Renal CancerNormal vs. CancertissueUp19164279

Hyperphosphorylation site
CRIP2_HUMAN do not have hyperphosphorylation site.

Direct Interaction Pair
SourceTargetRelationshipResource
KGP1_HUMANCRIP2_HUMANkinase -> substrateHPRD
KPCA_HUMANCRIP2_HUMANkinase -> substrateRobert H Newman (2013)

Function Annotation
KEGG Pathway
CRIP2_HUMAN is not in KEGG pathway.

Gene Ontology
GO IDGO_TermEvidenceOntology
GO:0005938cell cortexIEAcellular_component
GO:0008270zinc ion bindingIEAmolecular_function
GO:0030097hemopoiesisIEAbiological_process
GO:0031012extracellular matrixIDAcellular_component
GO:0008284positive regulation of cell proliferationIEAbiological_process
GO:0005515protein bindingIEAmolecular_function


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