| UniProt/SwissProt ID: | CRIP2_HUMAN |
| Description: | cysteine-rich protein 2 [Source:HGNC Symbol;Acc:2361] |
| Location: | chr14 q32.33 |
| Node attribute: | substrate |
| Phosphorylation site |
| Position | PhosphoPeptide | Catalytic kinase | Source |
|---|---|---|---|
| Y196 | GAVGSyIYDRD | PhosphoSitePlus; HPRD; SysPTM | |
| Y77 | AGSYIyEKPLA | PhosphoSitePlus; HPRD; phosphoELM | |
| T117 | RASSVtTFTGE | PhosphoSitePlus; HPRD; phosphoELM | |
| T88 | EGPQVtGPIEV | PhosphoSitePlus | |
| S115 | PSRASsVTTFT | PhosphoSitePlus; HPRD; phosphoELM | |
| Y198 | VGSYIyDRDPE | PhosphoSitePlus; HPRD; SysPTM | |
| S111 | PPKGPsRASSV | PhosphoSitePlus | |
| Y13 | CDKTVyFAEKV | zf-DNA_Pol; LIM | PhosphoSitePlus |
| Y134 | CSKKVyFAEKV | zf-DNA_Pol; LIM | PhosphoSitePlus |
| S104 | EERKAsGPPKG | PKG1 | RegPhos |
| Y75 | GGAGSyIYEKP | PhosphoSitePlus | |
| S104 | EERKAsGPPKG | PRKG1 | HPRD |
| S195 | TGAVGsYIYDR | PhosphoSitePlus | |
| S74 | IGGAGsYIYEK | PhosphoSitePlus | |
| S104 | EERKAsGPPKG | PKG1/cGK-I | phosphoELM |
| S114 | GPSRAsSVTTF | PhosphoSitePlus; HPRD | |
| Dephosphorylation site |
| CRIP2_HUMAN do not have dephosphorylation site. |
| Mutation site |
| CRIP2_HUMAN do not have mutation site. |
| Differential expressed protein |
| Ensembl ID | Cancer name | Design | Sample | Change | Ratio | Pubmed |
|---|---|---|---|---|---|---|
| ENSP00000328521 | Renal Cancer | Normal vs. Cancer | tissue | Up | 19164279 | |
| Hyperphosphorylation site |
| CRIP2_HUMAN do not have hyperphosphorylation site. |
| Direct Interaction Pair |
| Source | Target | Relationship | Resource |
|---|---|---|---|
| KGP1_HUMAN | CRIP2_HUMAN | kinase -> substrate | HPRD |
| KPCA_HUMAN | CRIP2_HUMAN | kinase -> substrate | Robert H Newman (2013) |
| Function Annotation |
| KEGG Pathway |
| CRIP2_HUMAN is not in KEGG pathway. |
| Gene Ontology |
| GO ID | GO_Term | Evidence | Ontology |
|---|---|---|---|
| GO:0005938 | cell cortex | IEA | cellular_component |
| GO:0008270 | zinc ion binding | IEA | molecular_function |
| GO:0030097 | hemopoiesis | IEA | biological_process |
| GO:0031012 | extracellular matrix | IDA | cellular_component |
| GO:0008284 | positive regulation of cell proliferation | IEA | biological_process |
| GO:0005515 | protein binding | IEA | molecular_function |