Protein information
  Protein summary    Phosphorylation site    Dephosphorylation site    Mutation site
  Differential expressed protein    Hyperphosphorylation site    Direct interaction pair    Function Annotation

Protein Summary
UniProt/SwissProt ID:CRFR2_HUMAN
Description:corticotropin releasing hormone receptor 2 [Source:HGNC Symbol;Acc:2358]
Location:chr7 p14.3
Node attribute:receptor; GPCR

Phosphorylation site
CRFR2_HUMAN do not have phosphorylation site.

Dephosphorylation site
CRFR2_HUMAN do not have dephosphorylation site.

Mutation site
CRFR2_HUMAN do not have mutation site.

Differential expressed protein
CRFR2_HUMAN is not differential expressed protein.

Hyperphosphorylation site
CRFR2_HUMAN do not have hyperphosphorylation site.

Direct Interaction Pair
SourceTargetRelationshipResource
UCN3_HUMANCRFR2_HUMANligand -> receptorHPMR
CRF_HUMANCRFR2_HUMANligand -> receptorHPMR
UCN2_HUMANCRFR2_HUMANligand -> receptorHPMR
UCN1_HUMANCRFR2_HUMANligand -> receptorHPMR
CRFR2_HUMANGNAS1_HUMANGPCR -> GproteingpDB
CRFR2_HUMANGNAS2_HUMANGPCR -> GproteingpDB

Function Annotation
KEGG Pathway
KEGG IDPathway
hsa04080Neuroactive ligand-receptor interaction

Gene Ontology
GO IDGO_TermEvidenceOntology
GO:0005179hormone activityIEAmolecular_function
GO:0005887integral to plasma membraneTAScellular_component
GO:0005886plasma membraneTAScellular_component
GO:0005794Golgi apparatusIEAcellular_component
GO:0016021integral to membraneIEAcellular_component
GO:0004888transmembrane signaling receptor activityIEAmolecular_function
GO:0015056corticotrophin-releasing factor receptor activityIEAmolecular_function
GO:0007188adenylate cyclase-modulating G-protein coupled recTASbiological_process
GO:0043950positive regulation of cAMP-mediated signalingIEAbiological_process
GO:0005515protein bindingIPImolecular_function
GO:0009986cell surfaceIEAcellular_component
GO:0005783endoplasmic reticulumIEAcellular_component
GO:0071376cellular response to corticotropin-releasing hormoIEAbiological_process
GO:0016525negative regulation of angiogenesisIEAbiological_process
GO:0007166cell surface receptor signaling pathwayIEAbiological_process
GO:0004930G-protein coupled receptor activityIEAmolecular_function
GO:0005515protein bindingIEAmolecular_function
GO:0007186G-protein coupled receptor signaling pathwayIEAbiological_process
GO:0043951negative regulation of cAMP-mediated signalingIEAbiological_process
GO:0016020membraneIEAcellular_component


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