| UniProt/SwissProt ID: | CP21A_HUMAN |
| Description: | cytochrome P450, family 21, subfamily A, polypeptide 2 [Source:HGNC Symbol;Acc:2600] |
| Location: | chrHSCHR6_MHC_MCF p2 |
| Node attribute: | gene |
| Phosphorylation site |
| Position | PhosphoPeptide | Catalytic kinase | Source |
|---|---|---|---|
| Y190 | NLMPAyYKCIQ | p450 | PhosphoSitePlus |
| T76 | LNSKRtIEEAM | p450 | PhosphoSitePlus |
| Dephosphorylation site |
| CP21A_HUMAN do not have dephosphorylation site. |
| Mutation site |
| CP21A_HUMAN do not have mutation site. |
| Differential expressed protein |
| Ensembl ID | Cancer name | Design | Sample | Change | Ratio | Pubmed |
|---|---|---|---|---|---|---|
| ENSP00000398594 | colorectal cancer | Normal vs. Cancer | tissue | Up | 3 | 15924290 |
| Hyperphosphorylation site |
| CP21A_HUMAN do not have hyperphosphorylation site. |
| Direct Interaction Pair |
| Source | Target | Relationship | Resource |
|---|---|---|---|
| SP1_HUMAN | CP21A_HUMAN | TF -> target gene | TRANSFAC |
| Function Annotation |
| KEGG Pathway |
| CP21A_HUMAN is not in KEGG pathway. |
| Gene Ontology |
| GO ID | GO_Term | Evidence | Ontology |
|---|---|---|---|
| GO:0004509 | steroid 21-monooxygenase activity | IEA | molecular_function |
| GO:0008202 | steroid metabolic process | TAS | biological_process |
| GO:0005789 | endoplasmic reticulum membrane | TAS | cellular_component |
| GO:0044281 | small molecule metabolic process | TAS | biological_process |
| GO:0005506 | iron ion binding | IEA | molecular_function |
| GO:0006805 | xenobiotic metabolic process | TAS | biological_process |
| GO:0006704 | glucocorticoid biosynthetic process | TAS | biological_process |
| GO:0016705 | oxidoreductase activity, acting on paired donors, | IEA | molecular_function |
| GO:0020037 | heme binding | IEA | molecular_function |
| GO:0006705 | mineralocorticoid biosynthetic process | TAS | biological_process |
| GO:0055114 | oxidation-reduction process | IEA | biological_process |
| GO:0009055 | electron carrier activity | IEA | molecular_function |
| GO:0005496 | steroid binding | IEA | molecular_function |
| GO:0008395 | steroid hydroxylase activity | TAS | molecular_function |