| UniProt/SwissProt ID: | CO5A2_HUMAN |
| Description: | collagen, type V, alpha 2 [Source:HGNC Symbol;Acc:2210] |
| Location: | chr2 q32.2 |
| Node attribute: | gene |
| Phosphorylation site |
| Position | PhosphoPeptide | Catalytic kinase | Source |
|---|---|---|---|
| T1281 | SSQIEtMRSPD | PhosphoSitePlus | |
| S1277 | LKSLSsQIETM | PhosphoSitePlus | |
| T575 | GARGLtGNPGV | Collagen | PhosphoSitePlus |
| S1276 | TLKSLsSQIET | PhosphoSitePlus | |
| T326 | GEAGPtGPMGA | Collagen | PhosphoSitePlus |
| S1284 | IETMRsPDGSK | COLFI | PhosphoSitePlus |
| Dephosphorylation site |
| CO5A2_HUMAN do not have dephosphorylation site. |
| Mutation site |
| Ensembl ID | Variation | Source | Cancer name | Pubmed |
|---|---|---|---|---|
| ENSP00000364000 | S1184L | BIOMART | Breast Cancer | 21930507, 21930502 | ENSP00000364000 | *1500W | COSMIC | Hepatocellular Carcinoma | ENSP00000364000 | G1164E | COSMIC | Skin Cancer | 21984974 | ENSP00000364000 | P659S | COSMIC | Ovarian Cancer | 21720365 | ENSP00000364000 | R1453Q | COSMIC | Ovarian Cancer | 21720365 | ENSP00000364000 | P1341S | BIOMART | Breast Cancer | 21930507, 21930502 |
| Differential expressed protein |
| CO5A2_HUMAN is not differential expressed protein. |
| Hyperphosphorylation site |
| CO5A2_HUMAN do not have hyperphosphorylation site. |
| Direct Interaction Pair |
| Source | Target | Relationship | Resource |
|---|---|---|---|
| HXB1_HUMAN | CO5A2_HUMAN | TF -> target gene | TRANSFAC |
| PBX1_HUMAN | CO5A2_HUMAN | TF -> target gene | TRANSFAC |
| PBX2_HUMAN | CO5A2_HUMAN | TF -> target gene | TRANSFAC |
| Function Annotation |
| KEGG Pathway |
| CO5A2_HUMAN is not in KEGG pathway. |
| Gene Ontology |
| GO ID | GO_Term | Evidence | Ontology |
|---|---|---|---|
| GO:0030199 | collagen fibril organization | ISS | biological_process |
| GO:0031012 | extracellular matrix | NAS | cellular_component |
| GO:0005515 | protein binding | IEA | molecular_function |
| GO:0046332 | SMAD binding | IEA | molecular_function |
| GO:0005576 | extracellular region | TAS | cellular_component |
| GO:0030198 | extracellular matrix organization | TAS | biological_process |
| GO:0001501 | skeletal system development | IEA | biological_process |
| GO:0071230 | cellular response to amino acid stimulus | IEA | biological_process |
| GO:0046872 | metal ion binding | IEA | molecular_function |
| GO:0007411 | axon guidance | TAS | biological_process |
| GO:0005201 | extracellular matrix structural constituent | IEA | molecular_function |
| GO:0005788 | endoplasmic reticulum lumen | TAS | cellular_component |
| GO:0003674 | molecular_function | ND | molecular_function |
| GO:0043588 | skin development | ISS | biological_process |
| GO:0005581 | collagen | IEA | cellular_component |
| GO:0005588 | collagen type V | IMP | cellular_component |
| GO:0043588 | skin development | IEA | biological_process |
| GO:0030199 | collagen fibril organization | IEA | biological_process |
| GO:0048592 | eye morphogenesis | IMP | biological_process |