Protein information
  Protein summary    Phosphorylation site    Dephosphorylation site    Mutation site
  Differential expressed protein    Hyperphosphorylation site    Direct interaction pair    Function Annotation

Protein Summary
UniProt/SwissProt ID:CLASR_HUMAN
Description:CLK4-associating serine/arginine rich protein [Source:HGNC Symbol;Acc:17731]
Location:chr19 q13.32
Node attribute:substrate

Phosphorylation site
PositionPhosphoPeptideCatalytic kinaseSource
S335TSFGGsDEEAAPhosphoSitePlus; HPRD
S649QSRSPsPRYSRPhosphoSitePlus
S505LSPSRsRSLTRPhosphoSitePlus
S642WERQYsRQSRSPhosphoSitePlus
S394TSSSRsSSRSSPhosphoSitePlus
S520QSPSPsPAREKphosphoELM
T319RSRSPtPGREEPhosphoSitePlus; HPRD
T389SSASRtSSSRSPhosphoSitePlus
S320TSFGGsDEEAAphosphoELM
S547TRPAAsPAVGEPhosphoSitePlus; HPRD
S309PSESSsESRSRHPRD
S195EEESNsDEDEVPhosphoSitePlus
S647SRQSRsPSPRYPhosphoSitePlus
S533RSQSPsPSPARPhosphoSitePlus
S288KISPPsYARRDPhosphoSitePlus; HPRD
S379RRRSSsSSSSSPhosphoSitePlus
S294YARRDsPTYDPPhosphoSitePlus; HPRD
Y228KQATTyGMADGPhosphoSitePlus
S518RSQSPsPSPARphosphoELM
S101LLTTIsPEQESHPRD
S516RSRSQsPSPSPphosphoELM
S381RSSSSsSSSSAPhosphoSitePlus
S308SPSESsSESRSHPRD
S305YKRSPsESSSEHPRD
T330KITFItSFGGSHPRD
S503WSLSPsRSRSLPhosphoSitePlus
S317RSRSRsPTPGRPhosphoSitePlus; HPRD
S421RSRSRsWSRSRPhosphoSitePlus; HPRD
T327REEKItFITSFPhosphoSitePlus; HPRD
S456HRYSRsPARRGPhosphoSitePlus
S502SWSLSpSRSRSHPRD
S515RSRSHsPSPSQPhosphoSitePlus
S435RRYSRsRSRGRHPRD
S501SSWSLsPSRSRPhosphoSitePlus; HPRD
S419HARSRsRSWSRPhosphoSitePlus; HPRD
Y652SPSPRySREYSPhosphoSitePlus
S390SASRTsSSRSSPhosphoSitePlus
S279YARRDsPTYDPphosphoELM
S423RSRSWsRSRSRPhosphoSitePlus; HPRD
Y432SRSRRySRSRSHPRD
S285RGRKIsPPSYAPhosphoSitePlus; HPRD
S382SSSSSsSSSASPhosphoSitePlus
S101LLTTIsPEQESDRY_EERYPhosphoSitePlus
S518SHSPSpSQSRSHPRD
T304RSRSPtPGREEphosphoELM
S535QSPSPsPAREKPhosphoSitePlus; HPRD
S514RSRSRsQSPSPphosphoELM
S270RGRKIsPPSYAphosphoELM
S395SSSRSsSRSSSPhosphoSitePlus
S302RSRSRsPTPGRphosphoELM
S512RSRSRsRSQSPphosphoELM
S391ASRTSsSRSSSPhosphoSitePlus
S510QSRSRsRSRSQphosphoELM
S531RSRSQsPSPSPPhosphoSitePlus; HPRD
S532TRPAAsPAVGEphosphoELM
S263EKAMYsGRRSRPhosphoSitePlus
S380RRSSSsSSSSSPhosphoSitePlus
S331ITFITsFGGSDPhosphoSitePlus; HPRD
S645QYSRQsRSPSPPhosphoSitePlus
S497SRSRSsWSLSPPhosphoSitePlus
S417GRHARsRSRSWPhosphoSitePlus
S180EEESNsDEDEVphosphoELM
S511RSLTRsRSHSPPhosphoSitePlus
S106SPEQEsDERKCHPRD
S267YSGRRsRRQRRPhosphoSitePlus

Dephosphorylation site
CLASR_HUMAN do not have dephosphorylation site.

Mutation site
Ensembl IDVariationSourceCancer namePubmed
ENSP00000221455H44RBIOMARTPancreatic Cancer21930507, 21930502
ENSP00000221455E626*BIOMARTHepatocellular Carcinoma21930507, 21930502
ENSP00000221455L213SHPIBreast Cancer16959974

Differential expressed protein
CLASR_HUMAN is not differential expressed protein.

Hyperphosphorylation site
CLASR_HUMAN do not have hyperphosphorylation site.

Direct Interaction Pair
SourceTargetRelationshipResource
PIM2_HUMANCLASR_HUMANkinase -> substrateRobert H Newman (2013)

Function Annotation
KEGG Pathway
CLASR_HUMAN is not in KEGG pathway.

Gene Ontology
GO IDGO_TermEvidenceOntology
GO:0008380RNA splicingIEAbiological_process
GO:0005634nucleusIEAcellular_component
GO:0006397mRNA processingIEAbiological_process


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