Protein information
  Protein summary    Phosphorylation site    Dephosphorylation site    Mutation site
  Differential expressed protein    Hyperphosphorylation site    Direct interaction pair    Function Annotation

Protein Summary
UniProt/SwissProt ID:CISH_HUMAN
Description:cytokine inducible SH2-containing protein [Source:HGNC Symbol;Acc:1984]
Location:chr3 p21.2
Node attribute:PPI(source)

Phosphorylation site
PositionPhosphoPeptideCatalytic kinaseSource
S175DTRSDsPDPAPPhosphoSitePlus
S173TADTRsDSPDPPhosphoSitePlus

Dephosphorylation site
CISH_HUMAN do not have dephosphorylation site.

Mutation site
Ensembl IDVariationSourceCancer namePubmed
ENSP00000294173E44QBIOMARTBreast Cancer21930507, 21930502

Differential expressed protein
CISH_HUMAN is not differential expressed protein.

Hyperphosphorylation site
CISH_HUMAN do not have hyperphosphorylation site.

Direct Interaction Pair
SourceTargetRelationshipResource
CISH_HUMANSTAT1_HUMANotherKEGG

Function Annotation
KEGG Pathway
KEGG IDPathway
hsa04630Jak-STAT signaling pathway

Gene Ontology
GO IDGO_TermEvidenceOntology
GO:0005575cellular_componentNDcellular_component
GO:0001558regulation of cell growthNASbiological_process
GO:0016567protein ubiquitinationIEAbiological_process
GO:0003674molecular_functionNDmolecular_function
GO:0005515protein bindingIEAmolecular_function
GO:0060397JAK-STAT cascade involved in growth hormone signalTASbiological_process
GO:0005829cytosolTAScellular_component
GO:0009968negative regulation of signal transductionIEAbiological_process
GO:0035556intracellular signal transductionNASbiological_process


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