| UniProt/SwissProt ID: | CHMP3_HUMAN |
| Description: | charged multivesicular body protein 3 [Source:HGNC Symbol;Acc:29865] |
| Location: | chr2 p11.2 |
| Node attribute: | substrate |
| Phosphorylation site |
| Position | PhosphoPeptide | Catalytic kinase | Source |
|---|---|---|---|
| T185 | APSKVtDALPE | Snf7 | PhosphoSitePlus |
| T126 | PEIQAtMRELS | Snf7 | PhosphoSitePlus |
| S134 | GAMAAsEDEEE | HPRD | |
| S116 | MKAMQsLVKIP | Snf7 | PhosphoSitePlus |
| T219 | QSRLAtLRS__ | PhosphoSitePlus | |
| S200 | GAMAAsEDEEE | PhosphoSitePlus; HPRD; SysPTM | |
| Dephosphorylation site |
| CHMP3_HUMAN do not have dephosphorylation site. |
| Mutation site |
| Ensembl ID | Variation | Source | Cancer name | Pubmed |
|---|---|---|---|---|
| ENSP00000386590 | *157S | COSMIC | Melanoma | 9354451 | ENSP00000263856 | A187V | COSMIC | Central Nervous System Neoplasms | 18772396 |
| Differential expressed protein |
| CHMP3_HUMAN is not differential expressed protein. |
| Hyperphosphorylation site |
| CHMP3_HUMAN do not have hyperphosphorylation site. |
| Direct Interaction Pair |
| Source | Target | Relationship | Resource |
|---|---|---|---|
| FAK2_HUMAN | CHMP3_HUMAN | kinase -> substrate | Robert H Newman (2013) |
| Function Annotation |
| KEGG Pathway |
| CHMP3_HUMAN is not in KEGG pathway. |
| Gene Ontology |
| GO ID | GO_Term | Evidence | Ontology |
|---|---|---|---|
| GO:0008333 | endosome to lysosome transport | IEA | biological_process |
| GO:0005770 | late endosome | IEA | cellular_component |
| GO:0005769 | early endosome | IEA | cellular_component |
| GO:0007049 | cell cycle | IEA | biological_process |
| GO:0051301 | cell division | IEA | biological_process |
| GO:0016044 | cellular membrane organization | TAS | biological_process |
| GO:0016197 | endosomal transport | TAS | biological_process |
| GO:0005515 | protein binding | IPI | molecular_function |
| GO:0005546 | phosphatidylinositol-4,5-bisphosphate binding | IEA | molecular_function |
| GO:0031902 | late endosome membrane | IEA | cellular_component |
| GO:0005829 | cytosol | TAS | cellular_component |
| GO:0006915 | apoptotic process | IEA | biological_process |
| GO:0051036 | regulation of endosome size | IEA | biological_process |
| GO:0015031 | protein transport | IEA | biological_process |
| GO:0030496 | midbody | IEA | cellular_component |
| GO:0000910 | cytokinesis | IEA | biological_process |