| UniProt/SwissProt ID: | CENPS_HUMAN |
| Description: | apoptosis-inducing, TAF9-like domain 1 [Source:HGNC Symbol;Acc:23163] |
| Location: | chr1 p36.22 |
| Node attribute: | substrate |
| Phosphorylation site |
| Position | PhosphoPeptide | Catalytic kinase | Source |
|---|---|---|---|
| S136 | AGVVEsEN___ | PhosphoSitePlus | |
| Y95 | NSLLKyITDKS | Serine_rich; TFIID-31kDa; | PhosphoSitePlus |
| S136 | AGVVEs | HPRD | |
| Dephosphorylation site |
| CENPS_HUMAN do not have dephosphorylation site. |
| Mutation site |
| CENPS_HUMAN do not have mutation site. |
| Differential expressed protein |
| CENPS_HUMAN is not differential expressed protein. |
| Hyperphosphorylation site |
| CENPS_HUMAN do not have hyperphosphorylation site. |
| Direct Interaction Pair |
| Source | Target | Relationship | Resource |
|---|---|---|---|
| CDK4_HUMAN | CENPS_HUMAN | kinase -> substrate | Robert H Newman (2013) |
| BUB1_HUMAN | CENPS_HUMAN | kinase -> substrate | Robert H Newman (2013) |
| WEE1_HUMAN | CENPS_HUMAN | kinase -> substrate | Robert H Newman (2013) |
| NEK3_HUMAN | CENPS_HUMAN | kinase -> substrate | Robert H Newman (2013) |
| FGFR2_HUMAN | CENPS_HUMAN | kinase -> substrate | Robert H Newman (2013) |
| Function Annotation |
| KEGG Pathway |
| CENPS_HUMAN is not in KEGG pathway. |
| Gene Ontology |
| GO ID | GO_Term | Evidence | Ontology |
|---|---|---|---|
| GO:0000278 | mitotic cell cycle | TAS | biological_process |
| GO:0005829 | cytosol | TAS | cellular_component |
| GO:0006974 | response to DNA damage stimulus | IMP | biological_process |
| GO:0003677 | DNA binding | IDA | molecular_function |
| GO:0051301 | cell division | IEA | biological_process |
| GO:0000712 | resolution of meiotic recombination intermediates | IMP | biological_process |
| GO:0046982 | protein heterodimerization activity | IEA | molecular_function |
| GO:0000777 | condensed chromosome kinetochore | IEA | cellular_component |
| GO:0043240 | Fanconi anaemia nuclear complex | IDA | cellular_component |
| GO:0006281 | DNA repair | IDA | biological_process |
| GO:0031297 | replication fork processing | IMP | biological_process |
| GO:0000236 | mitotic prometaphase | TAS | biological_process |
| GO:0006352 | DNA-dependent transcription, initiation | IEA | biological_process |
| GO:0071821 | FANCM-MHF complex | IDA | cellular_component |
| GO:0005515 | protein binding | IPI | molecular_function |
| GO:0031398 | positive regulation of protein ubiquitination | TAS | biological_process |
| GO:0000087 | M phase of mitotic cell cycle | TAS | biological_process |
| GO:0003682 | chromatin binding | IDA | molecular_function |
| GO:0003690 | double-stranded DNA binding | IDA | molecular_function |