Protein information
  Protein summary    Phosphorylation site    Dephosphorylation site    Mutation site
  Differential expressed protein    Hyperphosphorylation site    Direct interaction pair    Function Annotation

Protein Summary
UniProt/SwissProt ID:CDC23_HUMAN
Description:cell division cycle 23 [Source:HGNC Symbol;Acc:1724]
Location:chr5 q31.2
Node attribute:substrate

Phosphorylation site
PositionPhosphoPeptideCatalytic kinaseSource
T559GETPTtEVPAPCDC2(CDK1RegPhos
Y267QIAVAyHNIRDphosphoELM; RegPhos
S530LWDEAsTCAQKDUF772; TPR_2PhosphoSitePlus
S223MLKFLsLPDTWPhosphoSitePlus
S593SPLNLsSVTP_PhosphoSitePlus
S587SPLNLsSVphosphoELM
S594PLNLSsVTP__PhosphoSitePlus
S576FFLPAsLSANNPhosphoSitePlus; HPRD
S593SPLNLsSVHPRD
T596NLSSVtP____PhosphoSitePlus
Y273QIAVAyHNIRDPhosphoSitePlus
T559GETPTtEVPAPPLK1RegPhos
S594PLNLSsVHPRD
S304NMDTFsNLLYVHPRD
Y460CYWRAyAVGDVPhosphoSitePlus
Y308FSNLLyVRSMKHPRD
S587SPLNLsSVTPRegPhos
Y341VIGNYySLRSQTPR_1PhosphoSitePlus
T584ANNTPtRRVSPPhosphoSitePlus; HPRD
S588PLNLSsVTPRegPhos
T556RNQGEtPTTEVCDC2(CDK1RegPhos
T576LSANNtPTRRVCDK1phosphoELM
T558QGETPtTEVPAphosphoELM
T43LIAGLtRERGLAPC8PhosphoSitePlus
T559GETPTtEVPAPphosphoELM; RegPhos
T556RNQGEtPTTEVCDK1phosphoELM
S588PTRRVsPLNLSPhosphoSitePlus; HPRD
T576LSANNtPTRRVCDC2(CDK1RegPhos
T556RNQGEtPTTEVphosphoELM; RegPhos
T565GETPTtEVPAPPhosphoSitePlus; HPRD
Y353EKAALyFQRALTPR_1PhosphoSitePlus
T596NLSSVHPRD
S578LPASLsANNTPPhosphoSitePlus; HPRD
Y340CVIGNyYSLRSTPR_1PhosphoSitePlus
Y115NSKKAyFLYMYAPC8; Apc3PhosphoSitePlus
Y120YFLYMySRYLSAPC8; Apc3PhosphoSitePlus
S572LPASLsANNTPphosphoELM; RegPhos
T542CAFNDtREEGKPhosphoSitePlus
S582PTRRVsPLNLSphosphoELM; RegPhos; SysPTM
T590NLSSVphosphoELM
T576LSANNtPTRRVphosphoELM
T582LSANNtPTRRVPhosphoSitePlus; HPRD
S284IDKALsIFNELPhosphoSitePlus
Y329CEIDKyRVETCPhosphoSitePlus
S588PLNLSsVphosphoELM
T578ANNTPtRRVSPphosphoELM
T562RNQGEtPTTEVPhosphoSitePlus; HPRD
T564QGETPtTEVPAPhosphoSitePlus; HPRD
T590NLSSVtPRegPhos
S121FLYMYsRYLSGAPC8; Apc3PhosphoSitePlus
S570FFLPAsLSANNphosphoELM
T556RNQGEtPTTEVPLK1phosphoELM; RegPhos

Dephosphorylation site
CDC23_HUMAN do not have dephosphorylation site.

Mutation site
CDC23_HUMAN do not have mutation site.

Differential expressed protein
CDC23_HUMAN is not differential expressed protein.

Hyperphosphorylation site
CDC23_HUMAN do not have hyperphosphorylation site.

Direct Interaction Pair
SourceTargetRelationshipResource
PLK1_HUMANCDC23_HUMANkinase -> substrateRegPhos; Robert H Newman (2013)
ZAGL2_HUMANCDC23_HUMANkinase -> substrateRegPhos
CDK1_HUMANCDC23_HUMANkinase -> substrateRegPhos

Function Annotation
KEGG Pathway
KEGG IDPathway
hsa04110Cell cycle
hsa05166HTLV-I infection
hsa04114Oocyte meiosis
hsa04914Progesterone-mediated oocyte maturation
hsa04120Ubiquitin mediated proteolysis

Gene Ontology
GO IDGO_TermEvidenceOntology
GO:0007091mitotic metaphase/anaphase transitionTASbiological_process
GO:0051436negative regulation of ubiquitin-protein ligase acTASbiological_process
GO:0005654nucleoplasmTAScellular_component
GO:0005622intracellularIDAcellular_component
GO:0007049cell cycleTASbiological_process
GO:0030071regulation of mitotic metaphase/anaphase transitioIDAbiological_process
GO:0007080mitotic metaphase plate congressionIDAbiological_process
GO:0051439regulation of ubiquitin-protein ligase activity inTASbiological_process
GO:0000080G1 phase of mitotic cell cycleIDAbiological_process
GO:0007096regulation of exit from mitosisTASbiological_process
GO:0006511ubiquitin-dependent protein catabolic processTASbiological_process
GO:0005515protein bindingIEAmolecular_function
GO:0004842ubiquitin-protein ligase activityTASmolecular_function
GO:0000278mitotic cell cycleTASbiological_process
GO:0007067mitosisIDAbiological_process
GO:0070979protein K11-linked ubiquitinationIDAbiological_process
GO:0005680anaphase-promoting complexIDAcellular_component
GO:0007094mitotic cell cycle spindle assembly checkpointTASbiological_process
GO:0000075cell cycle checkpointTASbiological_process
GO:0005829cytosolTAScellular_component
GO:0051301cell divisionIEAbiological_process
GO:0051437positive regulation of ubiquitin-protein ligase acTASbiological_process
GO:0031145anaphase-promoting complex-dependent proteasomal uTASbiological_process


Fatal error: Uncaught Error: Call to undefined function mysql_close() in /usr/local/apache/htdocs/PhoSigNet/include/locateconfig.inc.php:23 Stack trace: #0 /usr/local/apache/htdocs/PhoSigNet/proteintable.php(435): db_disconnect(Object(mysqli)) #1 {main} thrown in /usr/local/apache/htdocs/PhoSigNet/include/locateconfig.inc.php on line 23