Protein information
  Protein summary    Phosphorylation site    Dephosphorylation site    Mutation site
  Differential expressed protein    Hyperphosphorylation site    Direct interaction pair    Function Annotation

Protein Summary
UniProt/SwissProt ID:CDC20_HUMAN
Description:cell division cycle 20 [Source:HGNC Symbol;Acc:1723]
Location:chr1 p34.2
Node attribute:substrate

Phosphorylation site
PositionPhosphoPeptideCatalytic kinaseSource
T466AAADEtLRLWRWD40PhosphoSitePlus
T164GSSRKtCRYIPPhosphoSitePlus
S41AGPAPsPMRAAPhosphoSitePlus; phosphoELM; SysPTM
S153LKVLYsQKATPPhosphoSitePlus
S161ATPGSsRKTCRPhosphoSitePlus
S92QMEVAsFLLSKBUB1HPRD; RegPhos
T106PENSQtPTKKEPhosphoSitePlus; phosphoELM; RegPhos
S170CRYIPsLPDRIPhosphoSitePlus
S51ANRSHsAGRTPPhosphoSitePlus
T69SSKVQtTPSKPPhosphoSitePlus
S92QMEVAsFLLSKPhosphoSitePlus
T59RTPGRtPGKSSPhosphoSitePlus
S161ATPGSsRKTCRBUB1HPRD; RegPhos
S153LKVLYsQKATPBUB1HPRD; RegPhos
S49RAANRsHSAGRPhosphoSitePlus
T157YSQKAtPGSSRBUB1HPRD; RegPhos
S72VQTTPsKPGGDBUB1HPRD; RegPhos
S72VQTTPsKPGGDPhosphoSitePlus; phosphoELM
T457SPDGAtVASAAWD40PhosphoSitePlus
T55HSAGRtPGRTPPhosphoSitePlus
T70SKVQTtPSKPGPhosphoSitePlus; HPRD; phosphoELM; RegPhos
Y152RLKVLySQKATPhosphoSitePlus
S448TSRVLsLTMSPWD40PhosphoSitePlus
T157YSQKAtPGSSRPhosphoSitePlus
Y79PGGDRyIPHRSPhosphoSitePlus; HPRD
S63RTPGKsSSKVQHPRD
S64TPGKSsSKVQTHPRD
S41AGPAPsPMRAABUB1HPRD; RegPhos; SysPTM

Dephosphorylation site
CDC20_HUMAN do not have dephosphorylation site.

Mutation site
Ensembl IDVariationSourceCancer namePubmed
ENSP00000361540A434DTCGAOvarian Cancer21720365, 18772890
ENSP00000308450A434DCOSMICOvarian Cancer21720365
ENSP00000308450A434DTCGAOvarian Cancer21720365, 18772890
ENSP00000361540A434DCOSMICOvarian Cancer21720365

Differential expressed protein
CDC20_HUMAN is not differential expressed protein.

Hyperphosphorylation site
CDC20_HUMAN do not have hyperphosphorylation site.

Direct Interaction Pair
SourceTargetRelationshipResource
BUB1_HUMANCDC20_HUMANkinase -> substrateRegPhos
ZAGL2_HUMANCDC20_HUMANkinase -> substrateRegPhos

Function Annotation
KEGG Pathway
KEGG IDPathway
hsa05203Viral carcinogenesis
hsa04120Ubiquitin mediated proteolysis
hsa05166HTLV-I infection
hsa04110Cell cycle
hsa04114Oocyte meiosis

Gene Ontology
GO IDGO_TermEvidenceOntology
GO:0000087M phase of mitotic cell cycleTASbiological_process
GO:0000278mitotic cell cycleTASbiological_process
GO:0005829cytosolTAScellular_component
GO:0008022protein C-terminus bindingIPImolecular_function
GO:0005654nucleoplasmTAScellular_component
GO:0040020regulation of meiosisIEAbiological_process
GO:0050773regulation of dendrite developmentIEAbiological_process
GO:0005515protein bindingIEAmolecular_function
GO:0090129positive regulation of synapse maturationISSbiological_process
GO:0051437positive regulation of ubiquitin-protein ligase acTASbiological_process
GO:0000236mitotic prometaphaseTASbiological_process
GO:0043234protein complexIEAcellular_component
GO:0090129positive regulation of synapse maturationIEAbiological_process
GO:0016567protein ubiquitinationIEAbiological_process
GO:0005680anaphase-promoting complexIDAcellular_component
GO:0005813centrosomeIEAcellular_component
GO:0019899enzyme bindingIPImolecular_function
GO:0051439regulation of ubiquitin-protein ligase activity inTASbiological_process
GO:0031915positive regulation of synaptic plasticityISSbiological_process
GO:0007094mitotic cell cycle spindle assembly checkpointTASbiological_process
GO:0005819spindleTAScellular_component
GO:0000922spindle poleIEAcellular_component
GO:0051436negative regulation of ubiquitin-protein ligase acTASbiological_process
GO:0051488activation of anaphase-promoting complex activityIDAbiological_process
GO:0005515protein bindingIPImolecular_function
GO:0031915positive regulation of synaptic plasticityIEAbiological_process
GO:0048471perinuclear region of cytoplasmIEAcellular_component
GO:0007049cell cycleTASbiological_process
GO:0008284positive regulation of cell proliferationIEAbiological_process
GO:0031145anaphase-promoting complex-dependent proteasomal uIDAbiological_process
GO:0000075cell cycle checkpointTASbiological_process
GO:0051301cell divisionIEAbiological_process


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