Protein information
  Protein summary    Phosphorylation site    Dephosphorylation site    Mutation site
  Differential expressed protein    Hyperphosphorylation site    Direct interaction pair    Function Annotation

Protein Summary
UniProt/SwissProt ID:CD97_HUMAN
Description:CD97 molecule [Source:HGNC Symbol;Acc:1711]
Location:chr19 p13.12
Node attribute:receptor

Phosphorylation site
PositionPhosphoPeptideCatalytic kinaseSource
S725FTSTTsGTGHNHPRD
T820STTSGtGHNQTHPRD
S738RALRAsESHPRD
S722YSEFTsTTSGTHPRD
S766YSEFTsTTSGTHPRD
S811GGSKYsEFTSTPhosphoSitePlus
S784LRASEsHPRD
S818FTSTTsGTGHNPhosphoSitePlus; HPRD
T727STTSGtGHNQTHPRD
S782RALRAsESHPRD
Y810AGGSKySEFTSPhosphoSitePlus
S815YSEFTsTTSGTPhosphoSitePlus; HPRD
S740LRASEsHPRD
S831RALRAsESHPRD; phosphoELM
T771STTSGtGHNQTHPRD
S831RALRAsESGI_PhosphoSitePlus
S833LRASEsHPRD; phosphoELM
T816SEFTStTSGTGPhosphoSitePlus
S769FTSTTsGTGHNHPRD
S833LRASEsGI___PhosphoSitePlus

Dephosphorylation site
CD97_HUMAN do not have dephosphorylation site.

Mutation site
Ensembl IDVariationSourceCancer namePubmed
ENSP00000242786A8PCOSMICBreast Cancer17932254
ENSP00000242786K281ICOSMICOvarian Cancer21720365
ENSP00000242786N406DCOSMICOvarian Cancer21720365
ENSP00000242786E431*COSMICOvarian Cancer20826764
ENSP00000242786P199LCOSMICHead and Neck Cancer21984974
ENSP00000349918K232ITCGAOvarian Cancer21720365, 18772890
ENSP00000349918N357DTCGAOvarian Cancer21720365, 18772890
ENSP00000242786S35ABIOMARTHepatocellular Carcinoma21930507, 21930502

Differential expressed protein
Ensembl IDCancer nameDesignSampleChangeRatioPubmed
ENSP00000242786Ovarian CancerTreatment (cisplatin-sensitive vs. cisplatin-resistant)cell lineUp4.319800108

Hyperphosphorylation site
CD97_HUMAN do not have hyperphosphorylation site.

Direct Interaction Pair
SourceTargetRelationshipResource
DAF_HUMANCD97_HUMANligand -> receptorHPMR

Function Annotation
KEGG Pathway
CD97_HUMAN is not in KEGG pathway.

Gene Ontology
GO IDGO_TermEvidenceOntology
GO:0005515protein bindingIEAmolecular_function
GO:0007218neuropeptide signaling pathwayIEAbiological_process
GO:0005886plasma membraneTAScellular_component
GO:0016021integral to membraneIEAcellular_component
GO:0016020membraneIEAcellular_component
GO:0006955immune responseTASbiological_process
GO:0007166cell surface receptor signaling pathwayTASbiological_process
GO:0004888transmembrane signaling receptor activityTASmolecular_function
GO:0005887integral to plasma membraneTAScellular_component
GO:0007155cell adhesionIEAbiological_process
GO:0004930G-protein coupled receptor activityIEAmolecular_function
GO:0006954inflammatory responseTASbiological_process
GO:0007186G-protein coupled receptor signaling pathwayTASbiological_process
GO:0005615extracellular spaceIEAcellular_component
GO:0005509calcium ion bindingIEAmolecular_function
GO:0007267cell-cell signalingTASbiological_process
GO:0006928cellular component movementTASbiological_process


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