Protein information
  Protein summary    Phosphorylation site    Dephosphorylation site    Mutation site
  Differential expressed protein    Hyperphosphorylation site    Direct interaction pair    Function Annotation

Protein Summary
UniProt/SwissProt ID:CD34_HUMAN
Description:CD34 molecule [Source:HGNC Symbol;Acc:1662]
Location:chr1 q32.2
Node attribute:ligand; gene

Phosphorylation site
PositionPhosphoPeptideCatalytic kinaseSource
S354AQGKAsVNRGACD34_antigenPhosphoSitePlus
Y330GEDPYyTENGGCD34_antigenPhosphoSitePlus
T331EDPYYtENGGGCD34_antigenPhosphoSitePlus
S198QNKTSsCAEFKCD34_antigenPhosphoSitePlus
S341GQGYSsGPGTSCD34_antigenPhosphoSitePlus
Y329LGEDPyYTENGCD34_antigenPhosphoSitePlus
Y339GGGQGySSGPGCD34_antigenPhosphoSitePlus

Dephosphorylation site
CD34_HUMAN do not have dephosphorylation site.

Mutation site
Ensembl IDVariationSourceCancer namePubmed
ENSP00000310036W317CCOSMICOvarian Cancer21720365

Differential expressed protein
CD34_HUMAN is not differential expressed protein.

Hyperphosphorylation site
CD34_HUMAN do not have hyperphosphorylation site.

Direct Interaction Pair
SourceTargetRelationshipResource
CD34_HUMANLYAM1_HUMANligand -> receptorHPMR
MZF1_HUMANCD34_HUMANTF -> target geneTRANSFAC

Function Annotation
KEGG Pathway
KEGG IDPathway
hsa04640Hematopoietic cell lineage
hsa04514Cell adhesion molecules (CAMs)

Gene Ontology
GO IDGO_TermEvidenceOntology
GO:0001935endothelial cell proliferationIDAbiological_process
GO:0045019negative regulation of nitric oxide biosynthetic pIDAbiological_process
GO:2001214positive regulation of vasculogenesisIDAbiological_process
GO:0005764lysosomeISScellular_component
GO:0036053glomerular endothelium fenestraISScellular_component
GO:0010629negative regulation of gene expressionIMPbiological_process
GO:0035759mesangial cell-matrix adhesionISSbiological_process
GO:0042482positive regulation of odontogenesisIDAbiological_process
GO:0005737cytoplasmIEAcellular_component
GO:0009897external side of plasma membraneIDAcellular_component
GO:0072254metanephric glomerular mesangial cell differentiatIEPbiological_process
GO:0005737cytoplasmIDAcellular_component
GO:0030195negative regulation of blood coagulationIDAbiological_process
GO:0009986cell surfaceIEAcellular_component
GO:0032720negative regulation of tumor necrosis factor produIDAbiological_process
GO:1900041negative regulation of interleukin-2 secretionIMPbiological_process
GO:0038001paracrine signalingIDAbiological_process
GO:1900038negative regulation of cellular response to hypoxiIDAbiological_process
GO:0071971extracellular vesicular exosome assemblyIDAbiological_process
GO:0071657positive regulation of granulocyte colony-stimulatIEPbiological_process
GO:0071425hematopoietic stem cell proliferationIMPbiological_process
GO:0050900leukocyte migrationISSbiological_process
GO:0061042vascular wound healingIEPbiological_process
GO:0008283cell proliferationISSbiological_process
GO:0060290transdifferentiationIEPbiological_process
GO:0045766positive regulation of angiogenesisIDAbiological_process
GO:0005886plasma membraneIDAcellular_component
GO:0016337cell-cell adhesionIDAbiological_process
GO:0008217regulation of blood pressureIDAbiological_process
GO:0001894tissue homeostasisIDAbiological_process
GO:0005887integral to plasma membraneTAScellular_component
GO:0032733positive regulation of interleukin-10 productionIDAbiological_process
GO:0010628positive regulation of gene expressionIEPbiological_process
GO:0003094glomerular filtrationIEPbiological_process
GO:1900035negative regulation of cellular response to heatIDAbiological_process
GO:0050776regulation of immune responseTASbiological_process
GO:0008134transcription factor bindingIPImolecular_function
GO:0016020membraneIEAcellular_component
GO:0016324apical plasma membraneISScellular_component
GO:0060547negative regulation of necrotic cell deathIDAbiological_process
GO:1900168positive regulation of glial cell line-derived neuIDAbiological_process
GO:0030246carbohydrate bindingIDAmolecular_function
GO:0071944cell peripheryIEAcellular_component
GO:0003158endothelium developmentIEPbiological_process
GO:0048870cell motilityIEPbiological_process
GO:0009925basal plasma membraneISScellular_component
GO:0072011glomerular endothelium developmentIEPbiological_process
GO:0030097hemopoiesisIMPbiological_process
GO:0048471perinuclear region of cytoplasmIDAcellular_component
GO:0045171intercellular bridgeIDAcellular_component
GO:0005576extracellular regionIEAcellular_component
GO:0072089stem cell proliferationIEPbiological_process
GO:0006536glutamate metabolic processIDAbiological_process
GO:0050900leukocyte migrationIEAbiological_process
GO:0007165signal transductionIEPbiological_process
GO:0043199sulfate bindingIEAmolecular_function
GO:0009897external side of plasma membraneIEAcellular_component
GO:0071636positive regulation of transforming growth factor IDAbiological_process