Protein information
  Protein summary    Phosphorylation site    Dephosphorylation site    Mutation site
  Differential expressed protein    Hyperphosphorylation site    Direct interaction pair    Function Annotation

Protein Summary
UniProt/SwissProt ID:CD226_HUMAN
Description:CD226 molecule [Source:HGNC Symbol;Acc:16961]
Location:chr18 q22.2
Node attribute:substrate; PPI(target)

Phosphorylation site
PositionPhosphoPeptideCatalytic kinaseSource
Y325DIYVNyPTFSRHerpes_gE; RCRPhosphoSitePlus
Y249KTDNQyTLFVAHerpes_gEPhosphoSitePlus
S329NYPTFsRRPKTRCRPhosphoSitePlus
Y322TREDIyVNYPTHerpes_gE; RCRPhosphoSitePlus; SysPTM
T293TESWDtQKAPNHerpes_gE; RCRPhosphoSitePlus
S329NYPTFsRRPKTPKC_alphaphosphoELM
T250TDNQYtLFVAGHerpes_gEPhosphoSitePlus
S329NYPTFsRRPKTPKCa(PKC alphaRegPhos
S290DLFTEsWDTQKHerpes_gE; RCRPhosphoSitePlus; SysPTM
Y322TREDIyVNYPTHPRD; phosphoELM; RegPhos; SysPTM
S313QPTNQsMDDTRHerpes_gE; RCRPhosphoSitePlus
S290DLFTEsWDTQKHPRD; phosphoELM; SysPTM

Dephosphorylation site
CD226_HUMAN do not have dephosphorylation site.

Mutation site
CD226_HUMAN do not have mutation site.

Differential expressed protein
CD226_HUMAN is not differential expressed protein.

Hyperphosphorylation site
CD226_HUMAN do not have hyperphosphorylation site.

Direct Interaction Pair
SourceTargetRelationshipResource
KPCA_HUMANCD226_HUMANkinase -> substrateRobert H Newman (2013)
ZAGL2_HUMANCD226_HUMANkinase -> substrateRegPhos
PVRL2_HUMANCD226_HUMANotherKEGG
PVR_HUMANCD226_HUMANotherKEGG

Function Annotation
KEGG Pathway
KEGG IDPathway
hsa04514Cell adhesion molecules (CAMs)

Gene Ontology
GO IDGO_TermEvidenceOntology
GO:0045121membrane raftTAScellular_component
GO:0005887integral to plasma membraneTAScellular_component
GO:0005515protein bindingIPImolecular_function
GO:0008037cell recognitionTASbiological_process
GO:0045954positive regulation of natural killer cell mediateIMPbiological_process
GO:0033005positive regulation of mast cell activationIDAbiological_process
GO:0001816cytokine productionIEAbiological_process
GO:0005886plasma membraneTAScellular_component
GO:0050839cell adhesion molecule bindingIPImolecular_function
GO:0019901protein kinase bindingIPImolecular_function
GO:0002891positive regulation of immunoglobulin mediated immIDAbiological_process
GO:0060369positive regulation of Fc receptor mediated stimulIDAbiological_process
GO:0050776regulation of immune responseTASbiological_process
GO:0005178integrin bindingIPImolecular_function
GO:0007155cell adhesionIEAbiological_process
GO:0009986cell surfaceIDAcellular_component
GO:0007165signal transductionTASbiological_process
GO:0002860positive regulation of natural killer cell mediateIMPbiological_process
GO:0005515protein bindingIEAmolecular_function


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