| UniProt/SwissProt ID: | CATG_HUMAN |
| Description: | cathepsin G [Source:HGNC Symbol;Acc:2532] |
| Location: | chr14 q12 |
| Node attribute: | PPI(source) |
| Phosphorylation site |
| Position | PhosphoPeptide | Catalytic kinase | Source |
|---|---|---|---|
| S233 | FTRVSsFLPWI | Trypsin | PhosphoSitePlus |
| Dephosphorylation site |
| CATG_HUMAN do not have dephosphorylation site. |
| Mutation site |
| Ensembl ID | Variation | Source | Cancer name | Pubmed |
|---|---|---|---|---|
| ENSP00000216336 | R239K | COSMIC | Skin Cancer | 21984974 | ENSP00000216336 | K246I | COSMIC | Ovarian Cancer | 21720365 |
| Differential expressed protein |
| Ensembl ID | Cancer name | Design | Sample | Change | Ratio | Pubmed |
|---|---|---|---|---|---|---|
| ENSP00000216336 | Uterine Cancer | Normal vs. Cancer | tissue | Up | 17902640 | |
| Hyperphosphorylation site |
| CATG_HUMAN do not have hyperphosphorylation site. |
| Direct Interaction Pair |
| Source | Target | Relationship | Resource |
|---|---|---|---|
| CATG_HUMAN | PAR1_HUMAN | other | KEGG |
| CATG_HUMAN | PRLHR_HUMAN | other | KEGG |
| CATG_HUMAN | MCHR1_HUMAN | other | KEGG |
| Function Annotation |
| KEGG Pathway |
| KEGG ID | Pathway |
|---|---|
| hsa05146 | Amoebiasis |
| hsa04614 | Renin-angiotensin system |
| hsa05322 | Systemic lupus erythematosus |
| hsa04142 | Lysosome |
| hsa04080 | Neuroactive ligand-receptor interaction |
| Gene Ontology |
| GO ID | GO_Term | Evidence | Ontology |
|---|---|---|---|
| GO:0009986 | cell surface | IEA | cellular_component |
| GO:0006955 | immune response | TAS | biological_process |
| GO:0050778 | positive regulation of immune response | IEA | biological_process |
| GO:0008233 | peptidase activity | IDA | molecular_function |
| GO:0005886 | plasma membrane | IDA | cellular_component |
| GO:0003824 | catalytic activity | IEA | molecular_function |
| GO:0030141 | secretory granule | IDA | cellular_component |
| GO:0030198 | extracellular matrix organization | TAS | biological_process |
| GO:0022617 | extracellular matrix disassembly | TAS | biological_process |
| GO:0006508 | proteolysis | IDA | biological_process |
| GO:0050830 | defense response to Gram-positive bacterium | IEA | biological_process |
| GO:0070946 | neutrophil mediated killing of gram-positive bacte | IEA | biological_process |
| GO:0044130 | negative regulation of growth of symbiont in host | IEA | biological_process |
| GO:0032496 | response to lipopolysaccharide | IEA | biological_process |
| GO:0008201 | heparin binding | IDA | molecular_function |
| GO:0031012 | extracellular matrix | IDA | cellular_component |
| GO:0050832 | defense response to fungus | IEA | biological_process |
| GO:0005576 | extracellular region | TAS | cellular_component |
| GO:0005615 | extracellular space | IDA | cellular_component |
| GO:0004252 | serine-type endopeptidase activity | IDA | molecular_function |