| UniProt/SwissProt ID: | CALL5_HUMAN |
| Description: | calmodulin-like 5 [Source:HGNC Symbol;Acc:18180] |
| Location: | chr10 p15.1 |
| Node attribute: | effector |
| Phosphorylation site |
| Position | PhosphoPeptide | Catalytic kinase | Source |
|---|---|---|---|
| Y136 | DGRVNyEEFAR | efhand | PhosphoSitePlus |
| T22 | FSAVDtDGNGT | efhand | PhosphoSitePlus |
| S18 | YKKAFsAVDTD | efhand | PhosphoSitePlus |
| T27 | TDGNGtINAQE | HPRD | |
| T27 | TDGNGtINAQE | efhand | PhosphoSitePlus |
| T22 | FSAVDtDGNGT | HPRD | |
| Y13 | EEEAQyKKAFS | efhand | PhosphoSitePlus |
| S18 | YKKAFsAVDTD | HPRD | |
| Dephosphorylation site |
| CALL5_HUMAN do not have dephosphorylation site. |
| Mutation site |
| Ensembl ID | Variation | Source | Cancer name | Pubmed |
|---|---|---|---|---|
| ENSP00000369689 | T99I | COSMIC | Skin Cancer | 21984974 | ENSP00000369689 | N25S | COSMIC | Ovarian Cancer | 21720365 |
| Differential expressed protein |
| Ensembl ID | Cancer name | Design | Sample | Change | Ratio | Pubmed |
|---|---|---|---|---|---|---|
| ENSP00000369689 | Breast Cancer | Metastasis | tissue | Up | 2.4 | 19053527 | ENSP00000369689 | Uterine Cancer | Treatment (Concurrent chemoradiotherapy-lowly vs. Concurrent chemoradiotherapy-highly sensitive) | tissue | Up | 19507834 |
| Hyperphosphorylation site |
| CALL5_HUMAN do not have hyperphosphorylation site. |
| Direct Interaction Pair |
| Source | Target | Relationship | Resource |
|---|---|---|---|
| GBG3_HUMAN | CALL5_HUMAN | Gprotein -> effector | gpDB |
| GBG2_HUMAN | CALL5_HUMAN | Gprotein -> effector | gpDB |
| GBG8_HUMAN | CALL5_HUMAN | Gprotein -> effector | gpDB |
| GBG5_HUMAN | CALL5_HUMAN | Gprotein -> effector | gpDB |
| GBB3_HUMAN | CALL5_HUMAN | Gprotein -> effector | gpDB |
| GBG12_HUMAN | CALL5_HUMAN | Gprotein -> effector | gpDB |
| GBG10_HUMAN | CALL5_HUMAN | Gprotein -> effector | gpDB |
| GBB1_HUMAN | CALL5_HUMAN | Gprotein -> effector | gpDB |
| GBG11_HUMAN | CALL5_HUMAN | Gprotein -> effector | gpDB |
| GBG1_HUMAN | CALL5_HUMAN | Gprotein -> effector | gpDB |
| GBB2_HUMAN | CALL5_HUMAN | Gprotein -> effector | gpDB |
| GBB5_HUMAN | CALL5_HUMAN | Gprotein -> effector | gpDB |
| GBG13_HUMAN | CALL5_HUMAN | Gprotein -> effector | gpDB |
| Function Annotation |
| KEGG Pathway |
| KEGG ID | Pathway |
|---|---|
| hsa05034 | Alcoholism |
| hsa05031 | Amphetamine addiction |
| hsa04740 | Olfactory transduction |
| hsa04720 | Long-term potentiation |
| hsa05214 | Glioma |
| hsa04270 | Vascular smooth muscle contraction |
| hsa04744 | Phototransduction |
| hsa05010 | Alzheimer's disease |
| hsa05133 | Pertussis |
| hsa04722 | Neurotrophin signaling pathway |
| hsa04910 | Insulin signaling pathway |
| hsa05152 | Tuberculosis |
| hsa04020 | Calcium signaling pathway |
| hsa04916 | Melanogenesis |
| hsa04971 | Gastric acid secretion |
| hsa04070 | Phosphatidylinositol signaling system |
| hsa04728 | Dopaminergic synapse |
| hsa04114 | Oocyte meiosis |
| hsa04912 | GnRH signaling pathway |
| hsa04970 | Salivary secretion |
| Gene Ontology |
| GO ID | GO_Term | Evidence | Ontology |
|---|---|---|---|
| GO:0007165 | signal transduction | TAS | biological_process |
| GO:0005509 | calcium ion binding | IEA | molecular_function |
| GO:0008544 | epidermis development | TAS | biological_process |
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