Protein information
  Protein summary    Phosphorylation site    Dephosphorylation site    Mutation site
  Differential expressed protein    Hyperphosphorylation site    Direct interaction pair    Function Annotation

Protein Summary
UniProt/SwissProt ID:CALC_HUMAN
Description:calcitonin-related polypeptide alpha [Source:HGNC Symbol;Acc:1437]
Location:chr11 p15.2
Node attribute:ligand

Phosphorylation site
PositionPhosphoPeptideCatalytic kinaseSource
S35SALESsPADPAPhosphoSitePlus
T105FNKFHtFPQTAPhosphoSitePlus
T41PADPAtLSEDEPhosphoSitePlus

Dephosphorylation site
CALC_HUMAN do not have dephosphorylation site.

Mutation site
Ensembl IDVariationSourceCancer namePubmed
ENSP00000331746P80SCOSMICCentral Nervous System Neoplasms18772890

Differential expressed protein
CALC_HUMAN is not differential expressed protein.

Hyperphosphorylation site
CALC_HUMAN do not have hyperphosphorylation site.

Direct Interaction Pair
SourceTargetRelationshipResource
CALC_HUMANCALCR_HUMANligand -> receptorHPMR
CALC_HUMANRAMP1_HUMANligand -> receptorHPMR
CALC_HUMANCALRL_HUMANligand -> receptorHPMR

Function Annotation
KEGG Pathway
CALC_HUMAN is not in KEGG pathway.

Gene Ontology
GO IDGO_TermEvidenceOntology
GO:0045779negative regulation of bone resorptionIDAbiological_process
GO:0007189adenylate cyclase-activating G-protein coupled recIEAbiological_process
GO:0032147activation of protein kinase activityIDAbiological_process
GO:0045762positive regulation of adenylate cyclase activityIDAbiological_process
GO:0005634nucleusIEAcellular_component
GO:0005576extracellular regionTAScellular_component
GO:0002027regulation of heart rateIEAbiological_process
GO:0007568agingIEAbiological_process
GO:0043005neuron projectionIEAcellular_component
GO:0007218neuropeptide signaling pathwayIEAbiological_process
GO:0050727regulation of inflammatory responseIEAbiological_process
GO:0043025neuronal cell bodyIEAcellular_component
GO:0031645negative regulation of neurological system processIEAbiological_process
GO:0005622intracellularIEAcellular_component
GO:0002548monocyte chemotaxisIDAbiological_process
GO:0045776negative regulation of blood pressureIEAbiological_process
GO:0005102receptor bindingIEAmolecular_function
GO:0048265response to painIEAbiological_process
GO:0001984vasodilation of artery involved in baroreceptor reIEAbiological_process
GO:0030424axonIEAcellular_component
GO:0051482elevation of cytosolic calcium ion concentration iIDAbiological_process
GO:0006954inflammatory responseIEAbiological_process
GO:0050965detection of temperature stimulus involved in sensIEAbiological_process
GO:0007631feeding behaviorIEAbiological_process
GO:0030279negative regulation of ossificationIEAbiological_process
GO:0042311vasodilationIEAbiological_process
GO:0005179hormone activityIEAmolecular_function
GO:0007204elevation of cytosolic calcium ion concentrationIDAbiological_process
GO:0045892negative regulation of transcription, DNA-dependenIDAbiological_process
GO:0031716calcitonin receptor bindingIPImolecular_function
GO:0045986negative regulation of smooth muscle contractionIEAbiological_process
GO:0009408response to heatIEAbiological_process
GO:0043195terminal buttonIEAcellular_component
GO:0005615extracellular spaceIDAcellular_component
GO:0045778positive regulation of ossificationIEAbiological_process
GO:0005737cytoplasmIEAcellular_component
GO:0008016regulation of heart contractionIEAbiological_process
GO:0005615extracellular spaceIEAcellular_component
GO:0006874cellular calcium ion homeostasisIEAbiological_process
GO:0007566embryo implantationIDAbiological_process


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