| UniProt/SwissProt ID: | C5ARL_HUMAN |
| Description: | complement component 5a receptor 2 [Source:HGNC Symbol;Acc:4527] |
| Location: | chr19 q13.32 |
| Node attribute: | receptor |
| Phosphorylation site |
| Position | PhosphoPeptide | Catalytic kinase | Source |
|---|---|---|---|
| S323 | DESVDsKKSTS | PhosphoSitePlus | |
| Dephosphorylation site |
| C5ARL_HUMAN do not have dephosphorylation site. |
| Mutation site |
| Ensembl ID | Variation | Source | Cancer name | Pubmed |
|---|---|---|---|---|
| ENSP00000257267 | A37S | BIOMART | Breast Cancer | 21930507, 21930502 | ENSP00000257267 | R300L | TCGA, COSMIC | Ovarian Cancer | 21720365, 18772890 |
| Differential expressed protein |
| C5ARL_HUMAN is not differential expressed protein. |
| Hyperphosphorylation site |
| C5ARL_HUMAN do not have hyperphosphorylation site. |
| Direct Interaction Pair |
| Source | Target | Relationship | Resource |
|---|---|---|---|
| CO5_HUMAN | C5ARL_HUMAN | ligand -> receptor | HPMR |
| Function Annotation |
| KEGG Pathway |
| C5ARL_HUMAN is not in KEGG pathway. |
| Gene Ontology |
| GO ID | GO_Term | Evidence | Ontology |
|---|---|---|---|
| GO:0005886 | plasma membrane | TAS | cellular_component |
| GO:0016021 | integral to membrane | IEA | cellular_component |
| GO:0004944 | C5a anaphylatoxin receptor activity | IEA | molecular_function |
| GO:0004930 | G-protein coupled receptor activity | IEA | molecular_function |
| GO:0007186 | G-protein coupled receptor signaling pathway | IEA | biological_process |
| GO:0005575 | cellular_component | ND | cellular_component |
| GO:0008150 | biological_process | ND | biological_process |
| GO:0006935 | chemotaxis | IEA | biological_process |
| GO:0005515 | protein binding | IPI | molecular_function |