Protein information
  Protein summary    Phosphorylation site    Dephosphorylation site    Mutation site
  Differential expressed protein    Hyperphosphorylation site    Direct interaction pair    Function Annotation

Protein Summary
UniProt/SwissProt ID:C2D1A_HUMAN
Description:coiled-coil and C2 domain containing 1A [Source:HGNC Symbol;Acc:30237]
Location:chr19 p13.12
Node attribute:substrate

Phosphorylation site
PositionPhosphoPeptideCatalytic kinaseSource
S238ATAPAsSPGLAHPRD; phosphoELM
S239TAPASsPGLAKHPRD; phosphoELM
S455PKKQNsPVAPTPhosphoSitePlus; HPRD; phosphoELM; SysPTM
S203GKGPAsTPTYSPhosphoSitePlus
T212YSPAPtQPAPRPhosphoSitePlus
T478SGSAPtAKAPPHPRD
T206PASTPtYSPAPPhosphoSitePlus
S208STPTYsPAPTQPhosphoSitePlus; HPRD; phosphoELM
S309EPVDLsCLPPPPhosphoSitePlus
Y916RQLQFyTEAARPhosphoSitePlus
T120QKASEtPPPVAPhosphoSitePlus; HPRD; phosphoELM
S179ENLLAsIRKGNPhosphoSitePlus; HPRD
T347PPPPRtLLEALPhosphoSitePlus
Y207ASTPTySPAPTPhosphoSitePlus; phosphoELM
Y937AKEALyRRNLVPhosphoSitePlus
S253PPGPCsPGPLAPhosphoSitePlus; HPRD; phosphoELM
T92DEEEGtDEDDLPhosphoSitePlus; HPRD
T204KGPAStPTYSPPhosphoSitePlus; HPRD; phosphoELM
S118EEQKAsETPPPHPRD; phosphoELM
S475TPQSGsAPTAKHPRD
S232TLEGPsATAPAHPRD

Dephosphorylation site
C2D1A_HUMAN do not have dephosphorylation site.

Mutation site
Ensembl IDVariationSourceCancer namePubmed
ENSP00000313601N940KBIOMARTBreast Cancer21930507, 21930502

Differential expressed protein
C2D1A_HUMAN is not differential expressed protein.

Hyperphosphorylation site
C2D1A_HUMAN do not have hyperphosphorylation site.

Direct Interaction Pair
SourceTargetRelationshipResource
ANPRB_HUMANC2D1A_HUMANkinase -> substrateRobert H Newman (2013)
DYRK4_HUMANC2D1A_HUMANkinase -> substrateRobert H Newman (2013)
KC1G2_HUMANC2D1A_HUMANkinase -> substrateRobert H Newman (2013)
NEK3_HUMANC2D1A_HUMANkinase -> substrateRobert H Newman (2013)

Function Annotation
KEGG Pathway
C2D1A_HUMAN is not in KEGG pathway.

Gene Ontology
GO IDGO_TermEvidenceOntology
GO:0005737cytoplasmIEAcellular_component
GO:0007165signal transductionIMPbiological_process
GO:0000122negative regulation of transcription from RNA polyIEAbiological_process
GO:0004871signal transducer activityIMPmolecular_function
GO:0005515protein bindingIEAmolecular_function
GO:0043123positive regulation of I-kappaB kinase/NF-kappaB cIMPbiological_process
GO:0001078RNA polymerase II core promoter proximal region seIEAmolecular_function
GO:0000978RNA polymerase II core promoter proximal region seIEAmolecular_function
GO:0005634nucleusIEAcellular_component
GO:0005815microtubule organizing centerIEAcellular_component


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