Protein information
  Protein summary    Phosphorylation site    Dephosphorylation site    Mutation site
  Differential expressed protein    Hyperphosphorylation site    Direct interaction pair    Function Annotation

Protein Summary
UniProt/SwissProt ID:C163A_HUMAN
Description:CD163 molecule [Source:HGNC Symbol;Acc:1631]
Location:chr12 p13.31
Node attribute:substrate

Phosphorylation site
PositionPhosphoPeptideCatalytic kinaseSource
S1084QRLAVsSRGENPKCaRegPhos
S1085RLAVSsRGENLP67870(Casein kinase II )RegPhos
S1084QRLAVsSRGENPRKCAHPRD
S14LEDSGsADFRRRegPhos
T1072ALFFLtKKRRQPRKCAHPRD
S1084QRLAVsSRGENPhosphoSitePlus
S1085RLAVSsRGENLCSNK2BHPRD
T1072ALFFLtKKRRQPKCaRegPhos

Dephosphorylation site
C163A_HUMAN do not have dephosphorylation site.

Mutation site
Ensembl IDVariationSourceCancer namePubmed
ENSP00000352071K640ECOSMICOvarian Cancer21720365
ENSP00000352071P310LCOSMICMelanoma20016485
ENSP00000403885A963SBIOMARTBreast Cancer21930507, 21930502
ENSP00000352071Q241HCOSMICOvarian Cancer21720365
ENSP00000352071G873ECOSMICOvarian Cancer21720365
ENSP00000352071A84GCOSMICOvarian Cancer21720365
ENSP00000352071L1057VCOSMICOvarian Cancer21720365
ENSP00000352071G1014DCOSMICOvarian Cancer21720365
ENSP00000352071A963SBIOMARTBreast Cancer21930507, 21930502
ENSP00000352071I1137NCOSMICSkin Cancer21984974

Differential expressed protein
Ensembl IDCancer nameDesignSampleChangeRatioPubmed
ENSP00000352071Gastric CancerMetastasiscell lineUp2.217022644
ENSP00000352071Gastric CancerMetastasiscell lineUp2.217022644
ENSP00000352071Ovarian CancerTreatment (chemotherapy-sensitive vs. chemotherapy-resistant)tissueUp219422301

Hyperphosphorylation site
C163A_HUMAN do not have hyperphosphorylation site.

Direct Interaction Pair
SourceTargetRelationshipResource
CSK2B_HUMANC163A_HUMANkinase -> substrateHPRD
ZAGL2_HUMANC163A_HUMANkinase -> substrateRegPhos
KPCA_HUMANC163A_HUMANkinase -> substrateHPRD

Function Annotation
KEGG Pathway
C163A_HUMAN is not in KEGG pathway.

Gene Ontology
GO IDGO_TermEvidenceOntology
GO:0005887integral to plasma membraneTAScellular_component
GO:0006953acute-phase responseIEAbiological_process
GO:0005515protein bindingIPImolecular_function
GO:0005044scavenger receptor activityNASmolecular_function
GO:0005576extracellular regionNAScellular_component
GO:0016020membraneIEAcellular_component


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