| UniProt/SwissProt ID: | BOC_HUMAN |
| Description: | BOC cell adhesion associated, oncogene regulated [Source:HGNC Symbol;Acc:17173] |
| Location: | chr3 q13.2 |
| Node attribute: | receptor |
| Phosphorylation site |
| Position | PhosphoPeptide | Catalytic kinase | Source |
|---|---|---|---|
| T483 | LSSPRtSKTDS | PhosphoSitePlus | |
| T486 | PRTSKtDSYEL | PhosphoSitePlus | |
| S488 | TSKTDsYELVW | PhosphoSitePlus | |
| Dephosphorylation site |
| BOC_HUMAN do not have dephosphorylation site. |
| Mutation site |
| Ensembl ID | Variation | Source | Cancer name | Pubmed |
|---|---|---|---|---|
| ENSP00000347546 | D302N | BIOMART | Pancreatic Cancer | 21930507, 21930502 | ENSP00000347546 | T721K | TCGA | Ovarian Cancer | 21720365, 18772890 | ENSP00000347546 | P322S | COSMIC | Central Nervous System Neoplasms | 18772396 | ENSP00000347546 | E34K | COSMIC | Pancreatic Cancer | ENSP00000347546 | I986F | COSMIC | Skin Cancer | 21984974 | ENSP00000347546 | P824S | COSMIC | Head and Neck Cancer | 21984974 | ENSP00000347546 | V713M | Sjoblom2006, COSMIC, HPI | Breast Cancer | 16959974 | ENSP00000418663 | P823T | TCGA | Ovarian Cancer | 21720365, 18772890 | ENSP00000347546 | P823T | TCGA | Ovarian Cancer | 21720365, 18772890 | ENSP00000347546 | T721K | COSMIC | Ovarian Cancer | 21720365 | ENSP00000418663 | V713M | HPI | Breast Cancer | 16959974 | ENSP00000347546 | G50R | COSMIC | Ovarian Cancer | 21720365 | ENSP00000347546 | P823T | COSMIC | Ovarian Cancer | 21720365 | ENSP00000418663 | T721K | TCGA | Ovarian Cancer | 21720365, 18772890 |
| Differential expressed protein |
| Ensembl ID | Cancer name | Design | Sample | Change | Ratio | Pubmed |
|---|---|---|---|---|---|---|
| ENSP00000347546 | Leukemia | Cancer vs. Cancer (chronic vs. acute leukemia) | cell line | Up | 17449014 | |
| Hyperphosphorylation site |
| BOC_HUMAN do not have hyperphosphorylation site. |
| Direct Interaction Pair |
| Source | Target | Relationship | Resource |
|---|---|---|---|
| SHH_HUMAN | BOC_HUMAN | ligand -> receptor | HPMR |
| Function Annotation |
| KEGG Pathway |
| BOC_HUMAN is not in KEGG pathway. |
| Gene Ontology |
| GO ID | GO_Term | Evidence | Ontology |
|---|---|---|---|
| GO:0030426 | growth cone | IEA | cellular_component |
| GO:0005515 | protein binding | IPI | molecular_function |
| GO:0005515 | protein binding | IEA | molecular_function |
| GO:0030030 | cell projection organization | IEA | biological_process |
| GO:0043025 | neuronal cell body | IEA | cellular_component |
| GO:0042692 | muscle cell differentiation | TAS | biological_process |
| GO:0051149 | positive regulation of muscle cell differentiation | TAS | biological_process |
| GO:0005886 | plasma membrane | TAS | cellular_component |
| GO:0030424 | axon | IEA | cellular_component |
| GO:0016021 | integral to membrane | IEA | cellular_component |
| GO:0007155 | cell adhesion | IEA | biological_process |
| GO:0007224 | smoothened signaling pathway | IEA | biological_process |
| GO:0007411 | axon guidance | IEA | biological_process |
| GO:0044295 | axonal growth cone | IEA | cellular_component |
| GO:0045663 | positive regulation of myoblast differentiation | IEA | biological_process |