Protein information
  Protein summary    Phosphorylation site    Dephosphorylation site    Mutation site
  Differential expressed protein    Hyperphosphorylation site    Direct interaction pair    Function Annotation

Protein Summary
UniProt/SwissProt ID:BMP6_HUMAN
Description:bone morphogenetic protein 6 [Source:HGNC Symbol;Acc:1073]
Location:chr6 p24.3
Node attribute:ligand

Phosphorylation site
BMP6_HUMAN do not have phosphorylation site.

Dephosphorylation site
BMP6_HUMAN do not have dephosphorylation site.

Mutation site
Ensembl IDVariationSourceCancer namePubmed
ENSP00000283147A343DSjoblom2006, COSMICIntestines Cancer16959974
ENSP00000283147A343DHPIColorectal Cancer16959974
ENSP00000283147Q110EBIOMARTHepatocellular Carcinoma21930507, 21930502
ENSP00000283147P476LSjoblom2006, COSMICIntestines Cancer16959974
ENSP00000283147P476LHPIColorectal Cancer16959974
ENSP00000283147H235RTCGAOvarian Cancer21720365, 18772890
ENSP00000283147H235RCOSMICOvarian Cancer21720365

Differential expressed protein
BMP6_HUMAN is not differential expressed protein.

Hyperphosphorylation site
BMP6_HUMAN do not have hyperphosphorylation site.

Direct Interaction Pair
SourceTargetRelationshipResource
BMP6_HUMANACVR1_HUMANligand -> receptorHPMR
BMP6_HUMANBMR1A_HUMANligand -> receptorHPMR

Function Annotation
KEGG Pathway
KEGG IDPathway
hsa04340Hedgehog signaling pathway
hsa04350TGF-beta signaling pathway

Gene Ontology
GO IDGO_TermEvidenceOntology
GO:0030539male genitalia developmentIEAbiological_process
GO:0005515protein bindingIEAmolecular_function
GO:0050679positive regulation of epithelial cell proliferatiIDAbiological_process
GO:0001822kidney developmentIEAbiological_process
GO:0001654eye developmentIEAbiological_process
GO:0006955immune responseIMPbiological_process
GO:0030509BMP signaling pathwayIEAbiological_process
GO:0030154cell differentiationIEAbiological_process
GO:0001958endochondral ossificationIEAbiological_process
GO:0045603positive regulation of endothelial cell differentiIEAbiological_process
GO:0045944positive regulation of transcription from RNA polyNASbiological_process
GO:0001938positive regulation of endothelial cell proliferatIEAbiological_process
GO:0040007growthIEAbiological_process
GO:0005125cytokine activityIEAmolecular_function
GO:0045669positive regulation of osteoblast differentiationIDAbiological_process
GO:0001649osteoblast differentiationIEAbiological_process
GO:0070700BMP receptor bindingIPImolecular_function
GO:0051216cartilage developmentIEAbiological_process
GO:0030501positive regulation of bone mineralizationIDAbiological_process
GO:0005615extracellular spaceIEAcellular_component
GO:0030509BMP signaling pathwayIDAbiological_process
GO:0045666positive regulation of neuron differentiationIEAbiological_process
GO:0005737cytoplasmIEAcellular_component
GO:0051384response to glucocorticoid stimulusIEAbiological_process
GO:0006954inflammatory responseIEAbiological_process
GO:0050714positive regulation of protein secretionNASbiological_process
GO:2000105positive regulation of DNA-dependent DNA replicatiNASbiological_process
GO:0003323type B pancreatic cell developmentIDAbiological_process
GO:0060395SMAD protein signal transductionIDAbiological_process
GO:0046982protein heterodimerization activityIDAmolecular_function
GO:0010862positive regulation of pathway-restricted SMAD proIDAbiological_process
GO:0008083growth factor activityIEAmolecular_function
GO:0032349positive regulation of aldosterone biosynthetic prIDAbiological_process
GO:0032526response to retinoic acidIEAbiological_process
GO:0001501skeletal system developmentTASbiological_process
GO:0031988membrane-bounded vesicleIEAcellular_component


Fatal error: Uncaught Error: Call to undefined function mysql_close() in /usr/local/apache/htdocs/PhoSigNet/include/locateconfig.inc.php:23 Stack trace: #0 /usr/local/apache/htdocs/PhoSigNet/proteintable.php(435): db_disconnect(Object(mysqli)) #1 {main} thrown in /usr/local/apache/htdocs/PhoSigNet/include/locateconfig.inc.php on line 23