Protein information
  Protein summary    Phosphorylation site    Dephosphorylation site    Mutation site
  Differential expressed protein    Hyperphosphorylation site    Direct interaction pair    Function Annotation

Protein Summary
UniProt/SwissProt ID:BMP2K_HUMAN
Description:BMP2 inducible kinase [Source:HGNC Symbol;Acc:18041]
Location:chr4 q21.21
Node attribute:kinase

Phosphorylation site
PositionPhosphoPeptideCatalytic kinaseSource
S14KSEGGsGGGAAPhosphoSitePlus
S1114HGSFHsADVLKPhosphoSitePlus
S979SLQKLsSRQRRPhosphoSitePlus; HPRD; SysPTM
S1111NSLHGsFHSADPhosphoSitePlus; HPRD
S728TGKKTsVQGQVPhosphoSitePlus
T1011KTLKPtYRTPEPhosphoSitePlus; HPRD; SysPTM
S697KKAEHsSINQEHPRD
S665DKNVDsLSAPHPhosphoSitePlus
S1031RRDSQsSNEFLPhosphoSitePlus; HPRD
S1076AKPFHsPDLSWPhosphoSitePlus; HPRD; SysPTM
S1080HSPDLsWHPPHPhosphoSitePlus
S949TSKSEsNEDLFHPRD
S10SRMPKsEGGSGHPRD
T1014KPTYRtPERARPhosphoSitePlus
S1041LTISDsKENISPhosphoSitePlus; HPRD
T935DVFGStPFQPFPhosphoSitePlus
T727RTGKKtSVQGQHPRD
S680EDPFGsVPFISHPRD
S947TSTSKsESNEDPhosphoSitePlus; HPRD
T829SGSGPtQDLNTPhosphoSitePlus
S687PFISHsGSPEKHPRD
S965DEITGsQQQKVHPRD
S980LQKLSsRQRRTPhosphoSitePlus
S974KVKQRsLQKLSPhosphoSitePlus
T383SATTAtPSVLTPhosphoSitePlus
Y820DMSSVyRDRSGPhosphoSitePlus
T1002HHGTPtSTKKTPhosphoSitePlus; HPRD; SysPTM
T1097RADHNtVLPGRPhosphoSitePlus
S1032RDSQSsNEFLTPhosphoSitePlus; HPRD; SysPTM
S1003HGTPTsTKKTLHPRD
T963PFDEItGSQQQHPRD
S378RPKANsATTATPhosphoSitePlus
S1107RPRQNsLHGSFPhosphoSitePlus; HPRD; phosphoELM; SysPTM
S1029VGRRDsQSSNEPhosphoSitePlus; HPRD; SysPTM
Y1012TLKPTyRTPERPhosphoSitePlus
S689ISHSGsPEKKAHPRD
Y257LGCLLyKLCFFPkinasePhosphoSitePlus
Y594IMDSSySANRSPhosphoSitePlus
S826RDRSGsGPTQDPhosphoSitePlus; HPRD; SysPTM
T834TQDLNtILLTSPhosphoSitePlus; HPRD
S685SVPFIsHSGSPHPRD
S824VYRDRsGSGPTPhosphoSitePlus; HPRD; SysPTM
Y257LGCLLyKLCFFHPRD
S843TSAQLsSDVAVPhosphoSitePlus
Y813QAKAKySDMSSPhosphoSitePlus

Dephosphorylation site
BMP2K_HUMAN do not have dephosphorylation site.

Mutation site
Ensembl IDVariationSourceCancer namePubmed
ENSP00000421768S580LBIOMARTPancreatic Cancer21930507, 21930502
ENSP00000421768*663GCOSMICHead and Neck Cancer21798893
ENSP00000334836T360SCOSMICOvarian Cancer21720365
ENSP00000334836S753IBIOMARTBreast Cancer21930507, 21930502
ENSP00000334836V68MHPILung Cancer17344846
ENSP00000421768T360STCGAOvarian Cancer21720365, 18772890

Differential expressed protein
BMP2K_HUMAN is not differential expressed protein.

Hyperphosphorylation site
BMP2K_HUMAN do not have hyperphosphorylation site.

Direct Interaction Pair
SourceTargetRelationshipResource
BMP2K_HUMANSSX2_HUMANkinase -> substrateRobert H Newman (2013)
BMP2K_HUMANZYX_HUMANkinase -> substrateRobert H Newman (2013)
BMP2K_HUMANZN784_HUMANkinase -> substrateRobert H Newman (2013)

Function Annotation
KEGG Pathway
BMP2K_HUMAN is not in KEGG pathway.

Gene Ontology
GO IDGO_TermEvidenceOntology
GO:0004672protein kinase activityIEAmolecular_function
GO:0030500regulation of bone mineralizationIEAbiological_process
GO:0006468protein phosphorylationIEAbiological_process
GO:0005634nucleusIEAcellular_component
GO:0004674protein serine/threonine kinase activityIEAmolecular_function
GO:0005524ATP bindingIEAmolecular_function
GO:0004713protein tyrosine kinase activityIEAmolecular_function
GO:0005634nucleusIDAcellular_component
GO:0019208phosphatase regulator activityIEAmolecular_function
GO:0016772transferase activity, transferring phosphorus-contIEAmolecular_function


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