Protein information
  Protein summary    Phosphorylation site    Dephosphorylation site    Mutation site
  Differential expressed protein    Hyperphosphorylation site    Direct interaction pair    Function Annotation

Protein Summary
UniProt/SwissProt ID:ARNT_HUMAN
Description:aryl hydrocarbon receptor nuclear translocator [Source:HGNC Symbol;Acc:700]
Location:chr1 q21.3
Node attribute:substrate

Phosphorylation site
PositionPhosphoPeptideCatalytic kinaseSource
S68DDDQMsNDKERPhosphoSitePlus; HPRD
S348LQVTSsPNCTDPhosphoSitePlus
T638QGATPtWTPTTPhosphoSitePlus
S669QFGVGsFQTPSPhosphoSitePlus
T636PTQGAtPTWTPPhosphoSitePlus
S788MFPPFsE____PhosphoSitePlus
S77ERFARsDDEQSPhosphoSitePlus; phosphoELM
T11ANPEMtSDVPSPhosphoSitePlus
S77ERFARsDDEQSCSNK2A1HPRD
S558RDPRFsEIYHNPhosphoSitePlus
T640ATPTWtPTTRSPhosphoSitePlus
Y561RFSEIyHNINAPhosphoSitePlus
T593NTFPPtPRPAEPhosphoSitePlus

Dephosphorylation site
ARNT_HUMAN do not have dephosphorylation site.

Mutation site
Ensembl IDVariationSourceCancer namePubmed
ENSP00000351407D238NCOSMICMelanoma21499247
ENSP00000351407C256YCOSMICLung Cancer20668451
ENSP00000351407P607SCOSMICCentral Nervous System Neoplasms18772890
ENSP00000351407G34RCOSMICLung Cancer20668451

Differential expressed protein
ARNT_HUMAN is not differential expressed protein.

Hyperphosphorylation site
ARNT_HUMAN do not have hyperphosphorylation site.

Direct Interaction Pair
SourceTargetRelationshipResource
CSK21_HUMANARNT_HUMANkinase -> substrateHPRD

Function Annotation
KEGG Pathway
KEGG IDPathway
hsa05200Pathways in cancer
hsa05211Renal cell carcinoma

Gene Ontology
GO IDGO_TermEvidenceOntology
GO:0005515protein bindingIEAmolecular_function
GO:0043619regulation of transcription from RNA polymerase IIIDAbiological_process
GO:0003705RNA polymerase II distal enhancer sequence-specifiIDAmolecular_function
GO:0046982protein heterodimerization activityIPImolecular_function
GO:0045893positive regulation of transcription, DNA-dependenIDAbiological_process
GO:0030522intracellular receptor mediated signaling pathwayIEAbiological_process
GO:0071456cellular response to hypoxiaTASbiological_process
GO:0045944positive regulation of transcription from RNA polyIEAbiological_process
GO:0046886positive regulation of hormone biosynthetic procesIDAbiological_process
GO:0017162aryl hydrocarbon receptor bindingIPImolecular_function
GO:0004874aryl hydrocarbon receptor activityIEAmolecular_function
GO:0033235positive regulation of protein sumoylationIEAbiological_process
GO:0005634nucleusIEAcellular_component
GO:0003700sequence-specific DNA binding transcription factorTASmolecular_function
GO:0005667transcription factor complexIEAcellular_component
GO:0007165signal transductionIEAbiological_process
GO:0033554cellular response to stressTASbiological_process
GO:0045821positive regulation of glycolysisICbiological_process
GO:0006351transcription, DNA-dependentTASbiological_process
GO:0043565sequence-specific DNA bindingIDAmolecular_function
GO:0042789mRNA transcription from RNA polymerase II promoterICbiological_process
GO:0003677DNA bindingIEAmolecular_function
GO:0000989transcription factor binding transcription factor IEAmolecular_function
GO:0046982protein heterodimerization activityIEAmolecular_function
GO:0045648positive regulation of erythrocyte differentiationICbiological_process
GO:0005737cytoplasmIEAcellular_component
GO:0005515protein bindingIPImolecular_function
GO:0001666response to hypoxiaIDAbiological_process
GO:0030949positive regulation of vascular endothelial growthICbiological_process
GO:0001938positive regulation of endothelial cell proliferatICbiological_process
GO:0008134transcription factor bindingIPImolecular_function
GO:0046983protein dimerization activityIEAmolecular_function
GO:0003713transcription coactivator activityIEAmolecular_function
GO:0001666response to hypoxiaIEAbiological_process
GO:0005654nucleoplasmTAScellular_component
GO:0010575positive regulation vascular endothelial growth faIDAbiological_process
GO:0001892embryonic placenta developmentIEAbiological_process
GO:0006355regulation of transcription, DNA-dependentIEAbiological_process
GO:0030154cell differentiationIEAbiological_process
GO:0005634nucleusIDAcellular_component
GO:0061418regulation of transcription from RNA polymerase IITASbiological_process
GO:0004871signal transducer activityIEAmolecular_function