Protein information
  Protein summary    Phosphorylation site    Dephosphorylation site    Mutation site
  Differential expressed protein    Hyperphosphorylation site    Direct interaction pair    Function Annotation

Protein Summary
UniProt/SwissProt ID:ARHG6_HUMAN
Description:Rac/Cdc42 guanine nucleotide exchange factor (GEF) 6 [Source:HGNC Symbol;Acc:685]
Location:chrX q26.3
Node attribute:PPI(target); PPI(source)

Phosphorylation site
PositionPhosphoPeptideCatalytic kinaseSource
S649YVIRKsTAALEPhosphoSitePlus; HPRD
T635LHKRKtERKPSPhosphoSitePlus
S126RSSSLsAANTSPhosphoSitePlus; HPRD
S640TERKPsEEEYVPhosphoSitePlus; HPRD
S123PCGRSsSLSAAPhosphoSitePlus; HPRD
S592KPWSLsCLRPAPhosphoSitePlus; HPRD
S122RPCGRsSSLSAPhosphoSitePlus; HPRD
S488ASPRMsGFIYQPHPhosphoSitePlus
S225SERPLsPKAVKPhosphoSitePlus; HPRD; phosphoELM
Y91DPDDLySGVNFCHPhosphoSitePlus
S669EAYCTsANFQQPhosphoSitePlus
Y188KGDIIyVTRVESH3_2PhosphoSitePlus
T650VIRKStAALEEHPRD
Y470EKEERyLMLFSHPRD
S684STRKDsIPQVLPhosphoSitePlus; HPRD; phosphoELM
S482VLIMLsASPRMHPRD
T701LIIEEtRSNGQPhosphoSitePlus
S622KESSKsPKTMKPhosphoSitePlus
T133ANTSQtNPQGAPhosphoSitePlus
T573SSFSStGQPRGPhosphoSitePlus
T717KSLVDtVYALKNsp1_CPhosphoSitePlus
T504AGTVVtRLDEIPHPhosphoSitePlus
S124CGRSSsLSAANPhosphoSitePlus; HPRD
S144VSSTVsGLQRQPhosphoSitePlus
Y719LVDTVyALKDENsp1_CPhosphoSitePlus
S562SKTSSsSCSAHPhosphoSitePlus
S484IMLSAsPRMSGHPRD
Y644PSEEEyVIRKSPhosphoSitePlus
S488ASPRMsGFIYQHPRD; phosphoELM
Y666KVIEAyCTSANPhosphoSitePlus
S454NVIFMsQVMVQHPRD
S150GLQRQsKTVEMPhosphoSitePlus; HPRD
Y614KERMSyILKESPhosphoSitePlus
S703IEETRsNGQTIPhosphoSitePlus

Dephosphorylation site
ARHG6_HUMAN do not have dephosphorylation site.

Mutation site
ARHG6_HUMAN do not have mutation site.

Differential expressed protein
ARHG6_HUMAN is not differential expressed protein.

Hyperphosphorylation site
ARHG6_HUMAN do not have hyperphosphorylation site.

Direct Interaction Pair
SourceTargetRelationshipResource
RRAS2_HUMANARHG6_HUMANotherKEGG
ARHG6_HUMANRAC1_HUMANotherKEGG

Function Annotation
KEGG Pathway
KEGG IDPathway
hsa04810Regulation of actin cytoskeleton
hsa05212Pancreatic cancer

Gene Ontology
GO IDGO_TermEvidenceOntology
GO:0030027lamellipodiumISScellular_component
GO:0005089Rho guanyl-nucleotide exchange factor activityNASmolecular_function
GO:0043547positive regulation of GTPase activityNASbiological_process
GO:0005096GTPase activator activityNASmolecular_function
GO:0005515protein bindingIPImolecular_function
GO:0051056regulation of small GTPase mediated signal transduTASbiological_process
GO:0030032lamellipodium assemblyIEAbiological_process
GO:0035023regulation of Rho protein signal transductionIEAbiological_process
GO:0006915apoptotic processNASbiological_process
GO:0048011nerve growth factor receptor signaling pathwayTASbiological_process
GO:0005622intracellularICcellular_component
GO:0007264small GTPase mediated signal transductionTASbiological_process
GO:0030032lamellipodium assemblyISSbiological_process
GO:0034329cell junction assemblyTASbiological_process
GO:0005829cytosolTAScellular_component
GO:0007254JNK cascadeNASbiological_process
GO:0005543phospholipid bindingIEAmolecular_function
GO:0005737cytoplasmIDAcellular_component
GO:0030027lamellipodiumIEAcellular_component


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