Protein information
  Protein summary    Phosphorylation site    Dephosphorylation site    Mutation site
  Differential expressed protein    Hyperphosphorylation site    Direct interaction pair    Function Annotation

Protein Summary
UniProt/SwissProt ID:ARC1B_HUMAN
Description:actin related protein 2/3 complex, subunit 1B, 41kDa [Source:HGNC Symbol;Acc:704]
Location:chr7 q22.1
Node attribute:substrate

Phosphorylation site
PositionPhosphoPeptideCatalytic kinaseSource
S330HKNSVsQISVLHPRD
T21WNKDRtQIAICTFIIIC_deltaPhosphoSitePlus
T21WNKDRtQIAICPAK1HPRD; RegPhos
S336QISVLsGGKAKHPRD
S310LDKKAsSEGGTPhosphoSitePlus; HPRD; phosphoELM; RegPhos; SysPTM
S311DKKASsEGGTAPhosphoSitePlus; HPRD; SysPTM
T297SQRGLtARERFPhosphoSitePlus
T89RTWKPtLVILRHPRD
S355MDGGMsIWDVKPhosphoSitePlus
S170KCRIFsAYIKERax2; WD40PhosphoSitePlus
S170KCRIFsAYIKEHPRD
T315SSEGGtAAGAGHPRD; phosphoELM; RegPhos; SysPTM
Y172RIFSAyIKEVEHPRD
Y172RIFSAyIKEVERax2PhosphoSitePlus
Y35HEVHIyEKSGATFIIIC_deltaPhosphoSitePlus
S328SLHKNsVSQISHPRD

Dephosphorylation site
ARC1B_HUMAN do not have dephosphorylation site.

Mutation site
ARC1B_HUMAN do not have mutation site.

Differential expressed protein
Ensembl IDCancer nameDesignSampleChangeRatioPubmed
ENSP00000389631Testicular CancerNormal vs. Cancercell lineUp18489135

Hyperphosphorylation site
ARC1B_HUMAN do not have hyperphosphorylation site.

Direct Interaction Pair
SourceTargetRelationshipResource
PKN1_HUMANARC1B_HUMANkinase -> substrateHPRD; RegPhos
ZAGL2_HUMANARC1B_HUMANkinase -> substrateRegPhos

Function Annotation
KEGG Pathway
KEGG IDPathway
hsa05132Salmonella infection
hsa05130Pathogenic Escherichia coli infection
hsa05131Shigellosis
hsa05100Bacterial invasion of epithelial cells
hsa04666Fc gamma R-mediated phagocytosis
hsa04810Regulation of actin cytoskeleton

Gene Ontology
GO IDGO_TermEvidenceOntology
GO:0005856cytoskeletonIEAcellular_component
GO:0005200structural constituent of cytoskeletonTASmolecular_function
GO:0030833regulation of actin filament polymerizationIEAbiological_process
GO:0005515protein bindingIEAmolecular_function
GO:0015629actin cytoskeletonTAScellular_component
GO:0005737cytoplasmIEAcellular_component
GO:0006928cellular component movementTASbiological_process
GO:0003779actin bindingIEAmolecular_function
GO:0005885Arp2/3 protein complexTAScellular_component


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